Central memory and effector memory T cell subsets: function, generation, and maintenance.
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Summary
This review addresses the heterogeneity of TCM and TEM, their differentiation stages, and the current models for their generation and maintenance in humans and mice.
- Type
- review
- Published
- 2004-03-19
- Cited by
- 3,299
- References
- 121
- OpenAlex
- https://openalex.org/W2113847305
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:37311371
Keywords
Effector, Biology, Homing (biology), Function (biology), Memory cell
References
- CCR5 is characteristic of Th1 lymphocytes
- Danger and OX40 Receptor Signaling Synergize to Enhance Memory T Cell Survival by Inhibiting Peripheral Deletion1
- Separable effector T cell populations specialized for B cell help or tissue inflammation
- Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation
- CD40 activation boosts T cell immunity in vivo by enhancing T cell clonal expansion and delaying peripheral T cell deletion.
- Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells
- CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes
- In Vivo Triggering Through 4-1BB Enables Th-Independent Priming of CTL in the Presence of an Intact CD28 Costimulatory Pathway1
- CD27 is required for generation and long-term maintenance of T cell immunity
- Help for cytotoxic-T-cell responses is mediated by CD40 signalling
- No one is naive: the significance of heterologous T-cell immunity
- Interleukin-7 mediates the homeostasis of naïve and memory CD8 T cells in vivo
- Visualizing the generation of memory CD4 T cells in the whole body
- Lifetime of plasma cells in the bone marrow
- A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1
- ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
- A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell
- T-cell help for cytotoxic T lymphocytes is mediated by CD40–CD40L interactions
- CCR7 Expression and Memory T Cell Diversity in Humans1
- Single IL-2-secreting precursor CD4 T cell can develop into either Th1 or Th2 cytokine secretion phenotype.
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- Differential expression of chemokine receptors and CD95 in porcine CD4(+) T cell subsets.
- The bone marrow: a nest for migratory memory T cells.
- Life and death of lymphocytes: a role in immunesenescence
- Mucosal effector memory T cells: the other side of the coin
- Effector memory T cells, early metastasis, and survival in colorectal cancer.
- A novel toxin from the venom of the scorpion Tityus trivittatus, is the first member of a new α‐KTX subfamily
- Susceptibility of naïve and subsets of memory T cells to apoptosis via multiple signaling pathways.
- Enhanced priming of adaptive immunity by a proapoptotic mutant of Mycobacterium tuberculosis.
- Bystander Central Memory but Not Effector Memory CD8+ T Cells Suppress Allograft Rejection1
- Administration of PLP139–151 Primes T Cells Distinct from Those Spontaneously Responsive In Vitro to This Antigen1
- T Cell Receptor Gene Therapy for Cancer
- Peripheral Blood CCR4+CCR6+ and CXCR3+CCR6+ CD4+ T Cells Are Highly Permissive to HIV-1 Infection
- Memory T-cell subsets in parasitic infections.
- Th17 central memory T cells are reduced by FTY720 in patients with multiple sclerosis
- Polyclonal expansion of human CD4(+)CD25(+) regulatory T cells.
- High Frequency of CD4+CXCR5+ TFH Cells in Patients with Immune-Active Chronic Hepatitis B
- Pharmacodynamic Effects of Steady‐State Fingolimod on Antibody Response in Healthy Volunteers: A 4‐Week, Randomized, Placebo‐Controlled, Parallel‐Group, Multiple‐Dose Study
- Human Immunodeficiency Virus (HIV) Latency: The Major Hurdle in HIV Eradication
- Antigen-Specific Memory T Cell Responses after Vaccination with an Oral Killed Cholera Vaccine in Bangladeshi Children and Comparison to Responses in Patients with Naturally Acquired Cholera
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