CCR7 Expression and Memory T Cell Diversity in Humans1
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Summary
It is found that CCR7 is expressed on the vast majority of peripheral blood T cells, including most cells that express adhesion molecules (cutaneous lymphocyte Ag α4β7 integrin) required for homing to nonlymphoid tissues.
- Type
- article
- Published
- 2001-01-15
- Cited by
- 384
- References
- 35
- Access
- Open access
- OpenAlex
- https://openalex.org/W1678352491
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9796225
Keywords
C-C chemokine receptor type 7, Homing (biology), Biology, Lymphocyte homing receptor, Cell biology
References
- Differential regulation of chemokine receptors during dendritic cell maturation: a model for their trafficking properties.
- Isolation of Human Intestinal Mucosal Mononuclear Cells
- Lymphocyte trafficking and regional immunity.
- Regulation of CD27 expression on subsets of mature T-lymphocytes.
- Cutting edge: developmental switches in chemokine responses during T cell maturation.
- Maturation and Trafficking of Monocyte-Derived Dendritic Cells in Monkeys: Implications for Dendritic Cell-Based Vaccines1
- Cutting edge: secondary lymphoid-tissue chemokine (SLC) and CC chemokine receptor 7 (CCR7) participate in the emigration pathway of mature dendritic cells from the skin to regional lymph nodes.
- CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs.
- Chemokines and cell migration in secondary lymphoid organs.
- Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
- Multistep Navigation and the Combinatorial Control of Leukocyte Chemotaxis
- The CD27− subset of peripheral blood memory CD4+ lymphocytes contains functionally differentiated T lymphocytes that develop by persistent antigenic stimulation in vivo
- A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes.
- Chemokines in tissue-specific and microenvironment-specific lymphocyte homing.
- Lymphocyte Homing and Homeostasis
- The amino terminus of human CCR5 is required for its function as a receptor for diverse human and simian immunodeficiency virus envelope glycoproteins.
- Integrating Conflicting Chemotactic Signals
- 6-C-kine (SLC), a Lymphocyte Adhesion-triggering Chemokine Expressed by High Endothelium, Is an Agonist for the MIP-3β Receptor CCR7
- Chemoattractant receptor cross talk as a regulatory mechanism in leukocyte adhesion and migration
- Dual personality of memory T cells.
Cited by
- Characteristics of CD4+CD25+ regulatory T cells in the peripheral circulation of patients with head and neck cancer
- Mucosal T lymphocytes—peacekeepers and warriors
- The bone marrow: a nest for migratory memory T cells.
- Differential expression of human granzymes A, B, and K in natural killer cells and during CD8+ T cell differentiation in peripheral blood
- Mucosal effector memory T cells: the other side of the coin
- Higher proportions of circulating FOXP3+ and CTLA-4+ regulatory T cells are associated with lower fractions of memory CD4+ T cells in infants
- A recombinant adenovirus expressing immunodominant TB antigens can significantly enhance BCG-induced human immunity.
- Specificity and plasticity of memory lymphocyte migration.
- Assessing the potential of hypochlorous acid-oxidised allogenic tumour cells as a source of antigen for dendritic cell-based immunotherapy of ovarian carcinoma
- Characterising lymphocyte trafficking across blood vascular and lymphatic endothelial cells
- Pathology of T-cell lymphomas: diagnosis and biomarker discovery.
- Immune maturation in early childhood and the influence of herpesvirus infections
- Immune reconstitution in paediatric patients with acquired immunodeficiency
- MAdCAM-1 expression and function in human liver.
- Analysis of CD45 variants effecting alternative splicing.
- Chemokine receptors expression on CD3+ blood cells in bronchial asthma.
- The association of sore throat and psoriasis might be explained by histologically distinctive tonsils and increased expression of skin‐homing molecules by tonsil T cells
- Breast Milk-Derived Antigen-Specific CD8+ T Cells: An Extralymphoid Effector Memory Cell Population in Humans1
- Monoclonal antibody TGN1412 trial failure explained by species differences in CD28 expression on CD4+ effector memory T‐cells
- Functional Expression of the Chemokine Receptor CCR5 on Virus Epitope-Specific Memory and Effector CD8+ T Cells1
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