Pulsed forces timed by a ratchet-like mechanism drive directed tissue movement during dorsal closure.
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Summary
A sophisticated mechanism of cooperative force generation between two major forces driving morphogenesis is uncovered in the developing Drosophila embryo, which involves tension-based dynamics and cell coupling and pulsed force pulses.
- Type
- article
- Published
- 2009-06-26
- Cited by
- 550
- References
- 40
- Access
- Open access
- OpenAlex
- https://openalex.org/W2100667554
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:14209028
Keywords
Epidermis (zoology), Biology, Ratchet, Dorsum, Mechanism (biology)
References
- Armadillo levels are reduced during mitosis in Drosophila.
- In vivo Selective Cytoskeleton Dynamics Quantification in Interphase Cells Induced by Pulsed Ultraviolet Laser Nanosurgery
- Drosophila APC2 and Armadillo participate in tethering mitotic spindles to cortical actin
- A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila.
- Drosophila Jun relays the Jun amino-terminal kinase signal transduction pathway to the Decapentaplegic signal transduction pathway in regulating epithelial cell sheet movement.
- Multiple Forces Contribute to Cell Sheet Morphogenesis for Dorsal Closure in Drosophila
- Pulsed actin-myosin network contractions drive apical constriction
- Transiently reorganized microtubules are essential for zippering during dorsal closure in Drosophila melanogaster.
- Nature and anisotropy of cortical forces orienting Drosophila tissue morphogenesis
- Specialized extraembryonic cells connect embryonic and extraembryonic epidermis in response to Dpp during dorsal closure in Drosophila.
- The control of cell motility and epithelial morphogenesis by Jun kinases.
- Mechanical feedback as a possible regulator of tissue growth.
- Dynamics of anisotropic tissue growth
- Actomyosin purse strings: Renewable resources that make morphogenesis robust and resilient
- JNK signaling coordinates integrin and actin functions during Drosophila embryogenesis
- Cortical actomyosin breakage triggers shape oscillations in cells and cell fragments.
- Shape oscillations of non-adhering fibroblast cells
- Ultraviolet diffraction limited nanosurgery of live biological tissues
- Common and distinct roles of DFos and DJun during Drosophila development.
- An amplified sensitivity arising from covalent modification in biological systems.
Cited by
- Structural Insights into the Shroom-Rock Interaction and the Regulation of the Actomyosin Cytoskeleton
- Mechanical induction in embryonic development and tumor growth integrative cues through molecular to multicellular interplay and evolutionary perspectives.
- Asymmetric distribution of Echinoid defines the epidermal leading edge during Drosophila dorsal closure
- Balancing forces: architectural control of mechanotransduction
- A Vertex Model of Drosophila Ventral Furrow Formation
- Microtubule-dependent balanced cell contraction and luminal-matrix modification accelerate epithelial tube fusion
- Modelling apical columnar epithelium mechanics from circumferential contractile fibres
- A study of epithelial cell delamination in Drosophila
- Stability and dynamics of cell-cell junctions.
- Adherens junctions and cadherins in Drosophila development.
- Shroom2 regulates endothelial morphogenesis and centrosome duplication through the specific sub-cellular recruitment of Rho-kinase
- Cortical forces in cell shape changes and tissue morphogenesis.
- Adherens junction assembly and function in the Drosophila embryo.
- Biophysical Mechanisms of Early Heart Morphogenesis
- The role of physics in epithelial homeostasis and development
- Investigating the molecular mechanism of Shroom-Rock interaction and its role in cellular and tissue morphogenesis
- Tension and epithelial morphogenesis in Drosophila early embryos.
- Experimental Control of Morphogenesis in Embryonic Tissues
- Analysis of ventral furrow formation in the Drosophila embryo using developmental genetics in combination with computational modelling
- Physical forces and mechanical waves during tissue growth
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