Viral recognition and type I interferon production by Toll-like receptor and an RNA helicase, RIG-I

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Summary

It is found that RIG-I is essential for induction of type I interferons (IFNs) after infection with RNA viruses in fibroblasts and myeloid dendritic cells (DCs), and the TLR system exert antiviral responses in a cell type specific manner.

Type
article
Published
2005-11-01
Cited by
2
References
24

Keywords

IRF3, TRIF, TLR3, RIG-I, Biology

References

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