A receptor-mediated pathway for cholesterol homeostasis.

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Summary

The approach was to apply the techniques of cell culture to unravel the postulated regulatory defect in FH, which led to the discovery of a cell surface receptor for a plasma cholesterol transport protein called low density lipoprotein (LDL) and to the elucidation of the mechanism by which this receptor mediates feedback control of cholesterol synthesis.

Type
review
Published
1986-04-04
Cited by
5,631
References
157

Keywords

Homeostasis, Receptor, Chemistry, Cholesterol, Cell biology

References

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