Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation
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Summary
It is shown here that this morphological change is closely associated with excision of nucleosome chains from nuclear chromatin, apparently through activation of an intracellular, but non-lysosomal, endonuclease.
- Type
- article
- Published
- 1980-04-10
- Cited by
- 4,747
- References
- 15
- OpenAlex
- https://openalex.org/W2084609653
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4318802
Keywords
Chromatin, Endonuclease, Programmed cell death, Nucleosome, Glucocorticoid
References
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- Steroid hormone actions in tissue culture cells and cell hybrids--their relation to human malignancies.
- A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid.
- Bleomycin causes release of nucleosomes from chromatin and chromosomes
- Chromatin sub-structure. The digestion of chromatin DNA at regularly spaced sites by a nuclear deoxyribonuclease.
- Corticosteroids and lymphoid cells.
- Solenoidal model for superstructure in chromatin.
- Isolation and purification of calcium and magnesium dependent endonuclease from rat liver nuclei.
- Properties of rapidly labelled deoxyribonucleic acid fragments isolated from the cytoplasm of primary cultures of embryonic mouse liver cells.
- Apoptosis: A Basic Biological Phenomenon with Wide-ranging Implications in Tissue Kinetics
- Further studies on the role of calcium in glucocorticoid-induced lymphocytolysis.
- Initiation of DNA synthesis in rat thymus: correlation of calcium-dependent initiation in thymocytes and in isolated thymus nuclei.
- A histochemical study of hypertrophy and ischaemic injury of rat liver with special reference to changes in lysosomes.
- Calcium dependence of glucocorticoid-induced lymphocytolysis.
- DNA degradation in terminally differentiating lens fiber cells from chick embryos.
Cited by
- A study of changes in protein expression in the membranes of cells undergoing apoptosis
- The 19-kilodalton adenovirus E1B transforming protein inhibits programmed cell death and prevents cytolysis by tumor necrosis factor alpha
- Thrombospondin cooperates with CD36 and the vitronectin receptor in macrophage recognition of neutrophils undergoing apoptosis.
- Tumor suppressor genes.
- Development of an Apoptosis Endonuclease Assay
- Oxidative stress in mitochondria: its relationship to cellular Ca2+ homeostasis, cell death, proliferation, and differentiation.
- IL-2 and IL-7 but not IL-12 protect natural killer cells from death by apoptosis and up-regulate bcl-2 expression.
- Nonspecific cytotoxic cells of rainbow trout (Oncorhynchus mykiss) kill YAC-1 targets by both necrotic and apoptic mechanisms.
- Intracellular Ca2+ and cytotoxicity.
- Helicobacter pylori and Acetylsalicylic Acid Synergistically Accelerate Apoptosis via Fas Antigen Pathway in Rabbit Gastric Epithelial Cells
- Mechanisms for programmed cell death in the nervous system of a moth.
- In vivo induction of apoptosis in human lymphocytes by therapeutic fractionated total body irradiation.
- Plasminogen Activator Inhibitor Type 2 Inhibits Tumor Necrosis Factor α-induced Apoptosis
- Demonstration of DNA damage/repair in individual cells using in situ end labelling: Association of p53 with sites of DNA damage
- Apoptotic cell death of a temperature-sensitive central neuronal cell line.
- Apoptosis in the repair process of experimental proliferative glomerulonephritis.
- Apoptosis: molecular mechanisms and implications for human disease
- Vitamin‐D3 derivatives and breast‐tumor cell growth: Effect on intracellular calcium and apoptosis
- The retinoblastoma protein-binding region of simian virus 40 large T antigen alters cell cycle regulation in lenses of transgenic mice
- Involution of the rat thymus in experimentally induced hypothyroidism
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