Plasminogen Activator Inhibitor Type 2 Inhibits Tumor Necrosis Factor α-induced Apoptosis
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Summary
The results suggest that intracellular PAI-2 might be an important factor in regulating cell death in T NF-mediated inflammatory processes through inhibition of a proteinase involved in TNF-induced apoptosis.
- Type
- article
- Published
- 1995-11-17
- Cited by
- 237
- References
- 66
- OpenAlex
- https://openalex.org/W7499264
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:36780133
Keywords
Computer science
References
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- Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis.
- Plasminogen activator inhibitor 2: regulation of gene transcription during phorbol ester-mediated differentiation of U-937 human histiocytic lymphoma cells
- Preparations of lymphotoxin induce resistance to their own cytotoxic effect.
Cited by
- The Serpins Are an Expanding Superfamily of Structurally Similar but Functionally Diverse Proteins
- Serpins and regulation of cell death.
- Malignant transformation of wild-type but not plasminogen activator inhibitor-1 gene-deficient fibroblasts decreases cellular sensitivity to chemotherapy-mediated apoptosis.
- Matrix degrading proteases in the ovary : expression and function
- Plasminogen activator inhibitor type 2 : a unique serpin with two mobile loops
- Plasminogen : a novel inflammatory regulator that promotes wound healing
- TNF-Induced Signaling in Apoptosis
- Plasminogen in periodontitis and wound repair
- Plasminogen activator inhibitor type 2: still an enigmatic serpin but a model for gene regulation.
- Applicability of toxicogenomics in molecular epidemiology : Gene expression profiling as a new biomarker
- Understanding the role of plasminogen activator inhibitor type-2 (PAI-2, SerpinB2) in cancer: the relationship between biochemical properties and cellular function
- The undecided serpin
- Viral inhibitors of apoptosis.
- Signal transduction pathways that regulate the fate of B lymphocytes.
- Fibrinolysis, inflammation, and regulation of the plasminogen activating system
- Current Concepts in Cell Toxicity
- Plasminogen activator inhibitor type 2 in human corneal epithelium.
- Serine protease inhibition and mitochondrial dysfunction associated with cisplatin resistance in human tumor cell lines: targets for therapy.
- Polymerisation underlies alpha1-antitrypsin deficiency, dementia and other serpinopathies.
- Characterisation of PAUSE-1, a powerful silencer in the human plasminogen activator inhibitor type 2 gene promoter.
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