Sensitization of TRAIL-resistant LNCaP cells by resveratrol (3, 4', 5 tri-hydroxystilbene): molecular mechanisms and therapeutic potential
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Summary
Resveratrol either alone or in combination with TRAIL or Smac can be used for the prevention and/or treatment of human prostate cancer.
- Type
- article
- Published
- 2007-08-24
- Cited by
- 96
- References
- 71
- Access
- Open access
- OpenAlex
- https://openalex.org/W2071255032
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:14405865
Keywords
Sensitization, Resveratrol, LNCaP, Medicine, Internal medicine
References
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- A model for p53-induced apoptosis
- Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models.
- Caspase-independent cell death
- [Mitochondrial control of apoptosis].
- Targeting Bcl-2 Related Proteins in Cancer Therapy
- The sequential treatment with ionizing radiation followed by TRAIL/Apo-2L reduces tumor growth and induces apoptosis of breast tumor xenografts in nude mice.
- Post-translational modification of p53 in tumorigenesis
- P53 and prognosis: new insights and further complexity.
- Enhancement of therapeutic potential of TRAIL by cancer chemotherapy and irradiation: mechanisms and clinical implications.
- J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential.
- Incidence of adenocarcinoma of the prostate in Asian immigrants to the United States and their descendants.
- The Pathophysiology of Mitochondrial Cell Death
- Cloning and Characterization of TRAIL-R3, a Novel Member of the Emerging TRAIL Receptor Family
- Activation of the p53 tumor suppressor protein.
- Ionizing radiation enhances the therapeutic potential of TRAIL in prostate cancer in vitro and in vivo: Intracellular mechanisms
- Inhibitor of Apoptosis Proteins Are Substrates for the Mitochondrial Serine Protease Omi/HtrA2*
Cited by
- Resveratrol prevention of oxidative stress damage to lens epithelial cell cultures is mediated by forkhead box O activity.
- Induction of p53 Phosphorylation at Serine 20 by Resveratrol Is Required to Activate p53 Target Genes, Restoring Apoptosis in MCF-7 Cells Resistant to Cisplatin
- Effets préventifs et sensibilisants du resvératrol dans le cancer
- Resveratrol in prostate diseases – a short review
- Mechanisms Associated with the Chemotherapeutic Effects of Zyflamend, a Multi-Herbal Extract, on Advanced Prostate Cancer
- Resveratrol: from basic studies to bedside.
- Upregulation of Death Receptor 5 and Production of Reactive Oxygen Species Mediate Sensitization of PC-3 Prostate Cancer Cells to TRAIL Induced Apoptosis by Vitisin A
- Resveratrol in prostate diseases
- Combination effect of equol and TRAIL against human cervical cancer cells.
- PRO-APOPTOTIC EFFECTS OF APPLE PROCYANIDINS IN HUMAN COLON CANCER CELLS AND THEIR DERIVED METASTATIC CELLS
- Phytochemicals As Chemosensitizers: From Molecular Mechanism to Clinical Significance
- Studies on search for bioactive natural products targeting TRAIL signaling leading to tumor cell apoptosis
- Effect of vicanicin and protolichesterinic acid on human prostate cancer cells: role of Hsp70 protein.
- Pentoxifylline augments TRAIL/Apo2L mediated apoptosis in cutaneous T cell lymphoma (HuT-78 and MyLa) by modulating the expression of antiapoptotic proteins and death receptors.
- Combining naturally occurring polyphenols with TNF-related apoptosis-inducing ligand: a promising approach to kill resistant cancer cells?
- Resveratrol Induces Growth Arrest and Apoptosis through Activation of FOXO Transcription Factors in Prostate Cancer Cells
- The anticancer effects of resveratrol – Modulation of transcription factors
- Chalcones Enhance TRAIL-Induced Apoptosis in Prostate Cancer Cells
- NutriTRAILomics in prostate cancer: time to have two strings to one’s bow
- Synergistic action of dietary phyto-antioxidants on survival and proliferation of ovarian cancer cells
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