Resveratrol prevention of oxidative stress damage to lens epithelial cell cultures is mediated by forkhead box O activity.
Explore this paper's citation graph
Summary
The levels of expression of FoxO1A, FoxO3A, and FoxO4 appear to play a central role in determining the pro- or anti-apoptotic effects of RES, which exerts a protective effect against oxidative damage in LEC cultures.
- Type
- article
- Published
- 2011-06-01
- Cited by
- 28
- References
- 33
- Access
- Open access
- OpenAlex
- https://openalex.org/W21345980
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13599559
Keywords
Victory, Front (military), Ancient history, Spanish Civil War, Political science
References
- Glutathione peroxidase-1 deficiency leads to increased nuclear light scattering, membrane damage, and cataract formation in gene-knockout mice.
- X-Ray induced cataract is preceded by LEC loss, and coincident with accumulation of cortical DNA, and ROS; similarities with age-related cataracts
- Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes
- Prevalence of canine cataract: preliminary results of a cross-sectional study.
- Normal mouse and rat strains as models for age-related cataract and the effect of caloric restriction on its development.
- A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span.
- Dietary caloric restriction may delay the development of cataract by attenuating the oxidative stress in the lenses of Brown Norway rats.
- SIRT1 is critical regulator of FOXO-mediated transcription in response to oxidative stress.
- Evidence for a Trade‐Off between Survival and Fitness Caused by Resveratrol Treatment of Caenorhabditis elegans
- dSir2 and longevity in Drosophila
- FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress.
- The Effect of Resveratrol in Experimental Cataract Model Formed by Sodium Selenite
- Sirtuin activators mimic caloric restriction and delay ageing in metazoans
- Sensitization of TRAIL-resistant LNCaP cells by resveratrol (3, 4', 5 tri-hydroxystilbene): molecular mechanisms and therapeutic potential
- Signal transduction by the JNK group of MAP kinases.
- Dietary Restriction, Growth Factors and Aging: from yeast to humans
- Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
- Dynamic FoxO transcription factors
- Free Radicals, Antioxidants and Eye Diseases: Evidence from Epidemiological Studies on Cataract and Age-Related Macular Degeneration
- Sir2 mediates apoptosis through JNK-dependent pathways in Drosophila
Cited by
- Pathological changes in hippocampal neuronal circuits underlie age-associated neurodegeneration and memory loss: positive clue toward SAD.
- Protective Effects of Resveratrol in Experimental Retinal Detachment
- Tanshinol Attenuates the Deleterious Effects of Oxidative Stress on Osteoblastic Differentiation via Wnt/FoxO3a Signaling
- FoxO3a Serves as a Biomarker of Oxidative Stress in Human Lens Epithelial Cells under Conditions of Hyperglycemia
- The effect of resveratrol on protecting corneal epithelial cells from cytotoxicity caused by moxifloxacin and benzalkonium chloride.
- Resveratrol preconditioning increases methionine sulfoxide reductases A expression and enhances resistance of human neuroblastoma cells to neurotoxins.
- Mitochondria-Targeted Antioxidant Peptide SS31 Protects Cultured Human Lens Epithelial Cells against Oxidative Stress
- Spatial expression patterns of autophagy genes in the eye lens and induction of autophagy in lens cells
- SIRT1 Protects Human Lens Epithelial Cells Against Oxidative Stress by Inhibiting p53-Dependent Apoptosis
- FOXO3a Activation by oxyresveratrol of Morus bombycis koidzumi extract mediates antioxidant activity
- Tanshinol Rescues the Impaired Bone Formation Elicited by Glucocorticoid Involved in KLF15 Pathway
- The Protective Effect of Curcumin on Ionizing Radiation-induced Cataractogenesis in Rats.
- Effects of Resveratrol on Crosstalk between Canonical Β-Catenin/Wnt and FOXO Pathways in Coronary Artery Disease Patients with Metabolic Syndrome: A Case Control Study
- A focus on resveratrol and ocular problems, especially cataract: From chemistry to medical uses and clinical relevance.
- The protective effect of beta-casomorphin-7 via promoting Foxo1 activity and nuclear translocation in human lens epithelial cells
- Evaluation of the early term healing effects of resveratrol on corneal wounds in rats
- New Highlights of Resveratrol: A Review of Properties against Ocular Diseases
- FOXO4 mediates resistance to oxidative stress in lens epithelial cells by modulating the TRIM25/Nrf2 signaling.
- Recent progress and research trend of anti-cataract pharmacology therapy: A bibliometric analysis and literature review.
- Breaking Barriers: Nanomedicine-Based Drug Delivery for Cataract Treatment
Related papers
No related papers recorded.