The Cancer Stem Cell Niche: How Essential is the Niche in Regulating Stemness of Tumor Cells?
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Summary
This work focuses on the CSC niche and discusses its contribution to tumor initiation and progression and examines the prospects of targeting the niche components as preferable therapeutic targets.
- Type
- review
- Published
- 2015-03-05
- Cited by
- 1,400
- References
- 162
- Access
- Open access
- OpenAlex
- https://openalex.org/W2071123870
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3037147
Keywords
Biology, Cancer stem cell, Niche, Tumor initiation, Ecological niche
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- Nanomedicine-mediated cancer stem cell therapy.
- Expression of Vascular Endothelial-Cadherin in Mucoepidermoid Carcinoma: Role in Cancer Development
- Thyroid hormone negatively regulates tumorigenesis through suppression of BC200.
- Chronic Traumatic Encephalopathy: The Neuropathological Legacy of Traumatic Brain Injury
- Characteristics of liver cancer stem cells and clinical correlations.
- Co-delivery of platinum drug and siNotch1 with micelleplex for enhanced hepatocellular carcinoma therapy.
- Galectin 3 as a guardian of the tumor microenvironment.
- Nanomaterials—Tools, Technology and Methodology of Nanotechnology Based Biomedical Systems for Diagnostics and Therapy
- Extracellular Vesicles: Evolving Factors in Stem Cell Biology
- The Role of Stroma in Tumor Development
- Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis
- lnflammation-induced epigenetic switches in cancer
- Targeting Head and Neck Cancer Stem Cells
- A paired comparison between glioblastoma “stem cells” and differentiated cells
- Cancer stem cell targeted therapy: progress amid controversies
- Application of single-cell genomics in cancer: promise and challenges
- Bypassing Mechanisms of Mitochondria-Mediated Cancer Stem Cells Resistance to Chemo- and Radiotherapy
- Cancer Stem Cells: Basic Concepts and Therapeutic Implications.
- A new insight into cancer stem cell markers: Could local and circulating cancer stem cell markers correlate in colorectal cancer?
- Tumor Twitter: Cellular Communication in the Breast Cancer Stem Cell Niche
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