Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface.

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Summary

Foreign DNA fragments can be inserted into filamentous phage gene III to create a fusion protein with the foreign sequence in the middle that is incorporated into the virion, which retains infectivity and displays the foreign amino acids in immunologically accessible form.

Type
article
Published
1985-06-14
Cited by
4,056
References
14

Keywords

Phagemid, Phage display, Fusion protein, Cloning (programming), Gene

References

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