Stability and flexibility of epigenetic gene regulation in mammalian development
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Summary
During development, cells start in a pluripotent state, from which they can differentiate into many cell types, and progressively develop a narrower potential, and their gene-expression programmes become more defined, restricted and, potentially, 'locked in'.
- Type
- review
- Published
- 2007-05-24
- Cited by
- 2,078
- References
- 68
- OpenAlex
- https://openalex.org/W2069717852
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11794102
Keywords
Epigenetics, Biology, Epigenetic regulation of neurogenesis, DNA methylation, Gene silencing
References
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