S100A8 Contributes to Drug Resistance by Promoting Autophagy in Leukemia Cells
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Summary
It is demonstrated that S100A8 is involved in the development of chemoresistance in leukemia cells by regulating autophagy, and suggested that S 100A8 may be a novel target for improving leukemia therapy.
- Published
- 2014-05-12
- Cited by
- 77
- References
- 42
- Access
- Open access
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7211091
References
- The S100 family of EF-hand calcium-binding proteins: functions and pathology.
- Eaten alive: a history of macroautophagy
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
- RAGE (receptor for advanced glycation end products): a central player in the inflammatory response.
- Autophagy Inhibition Enhances Daunorubicin-Induced Apoptosis in K562 Cells
- Expression of S100 proteins in normal human tissues and common cancers using tissue microarrays: S100A6, S100A8, S100A9 and S100A11 are all overexpressed in common cancers
- DAMP-mediated autophagy contributes to drug resistance
- Targeted inhibition of mTORC1 and mTORC2 by active-site mTOR inhibitors has cytotoxic effects in T-cell acute lymphoblastic leukemia
- Targeting microRNA-30a-mediated autophagy enhances imatinib activity against human chronic myeloid leukemia cells
- Effect of cromolyn on S100P interactions with RAGE and pancreatic cancer growth and invasion in mouse models.
- p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy*
- Self-eating and self-killing: crosstalk between autophagy and apoptosis
- Elevated S100A8/S100A9 expression causes glucocorticoid resistance in MLL-rearranged infant acute lymphoblastic leukemia
- Expression of S100A8 in leukemic cells predicts poor survival in de novo AML patients
- S100A8-targeting siRNA enhances arsenic trioxide-induced myeloid leukemia cell death by down-regulating autophagy.
- Myeloid related proteins activate Toll-like receptor 4 in human acute coronary syndromes.
- Methods in Mammalian Autophagy Research
- S100 proteins expressed in phagocytes: a novel group of damage‐associated molecular pattern molecules
- S100A9/S100A8: Myeloid representatives of the S100 protein family as prominent players in innate immunity
- The Beclin 1 network regulates autophagy and apoptosis
Cited by
- Benzyl butyl phthalate increases the chemoresistance to doxorubicin/cyclophosphamide by increasing breast cancer-associated dendritic cell-derived CXCL1/GROα and S100A8/A9.
- You eat what you are: autophagy inhibition as a therapeutic strategy in leukemia
- A case of EGFR mutant lung adenocarcinoma that acquired resistance to EGFR-tyrosine kinase inhibitors with MET amplification and epithelial-to-mesenchymal transition
- Effect of pantoprazole to enhance activity of docetaxel against human tumour xenografts by inhibiting autophagy
- DAMPs, Ageing, and Cancer: The ‘DAMP Hypothesis’
- Comparative proteomics analysis of differential proteins in respond to doxorubicin resistance in myelogenous leukemia cell lines
- Influence of the proton pump inhibitor lansoprazole on distribution and activity of doxorubicin in solid tumors
- Autophagy-related genes Raptor, Rictor, and Beclin1 expression and relationship with multidrug resistance in colorectal carcinoma.
- The Multiple Faces of RAGE - Opportunities for Therapeutic Intervention in Aging and Chronic Disease
- HMGB1, S100 proteins and other RAGE ligands in cancer - markers, mediators and putative therapeutic targets.
- Enhanced autophagy in cytarabine arabinoside-resistant U937 leukemia cells and its potential as a target for overcoming resistance
- Altered expression of autophagy‐related genes might contribute to glucocorticoid resistance in precursor B‐cell‐type acute lymphoblastic leukemia
- HnRNP K contributes to drug resistance in acute myeloid leukemia through the regulation of autophagy.
- Methylation of S100A8 is a promising diagnosis and prognostic marker in hepatocellular carcinoma
- Comparative proteomic profiling of refractory/relapsed multiple myeloma reveals biomarkers involved in resistance to bortezomib-based therapy
- Network-based expression analysis reveals key genes related to glucocorticoid resistance in infant acute lymphoblastic leukemia
- Autophagy, a key mechanism of oncogenesis and resistance in leukemia.
- Autophagy as a Survival Mechanism for Tumor Cells Exposed to Chemotherapy or Hypoxia, and its Inhibition by Pantoprazole to Improve Outcome of Treatment
- Meta-analysis of gene expression in relapsed childhood B-acute lymphoblastic leukemia
- Comparative proteomic analysis of the influence of gender and acid stimulation on normal human saliva using LC/MS/MS
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