p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy*

Explore this paper's citation graph

Summary

It is demonstrated that the previously reported aggresome-like induced structures containing ubiquitinated proteins in cytosolic bodies are dependent on p62 for their formation and p62 is required both for the formation and the degradation of polyubiquitin-containing bodies by autophagy.

Type
article
Published
2007-08-17
Cited by
4,567
References
56
Access
Open access

Keywords

ATG8, Autophagy, Ubiquitin, Degradation (telecommunications), Cell biology

References

Cited by

Related papers