Glucocorticoid resistance in asthma is associated with elevated in vivo expression of the glucocorticoid receptor β-isoform

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Summary

Because glucocorticoid receptor β inhibits α-glucocortin-driven cutaneous cell–mediated transactivation of target genes, the increased expression of glucocortsolone receptor β in inflammatory cells might be a critical mechanism for conferring glucoc Corticoid resistance.

Type
article
Published
2000-05-01
Cited by
284
References
19

Keywords

Glucocorticoid receptor, Glucocorticoid, Endocrinology, Internal medicine, Prednisolone

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