Causes and Consequences of Replication Stress
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- Type
- review
- Published
- 2013-12-24
- Cited by
- 1,919
- References
- 140
- OpenAlex
- https://openalex.org/W2040860750
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11260968
Keywords
Cell biology, DNA replication, Biology, Genome instability, DNA re-replication
References
- R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants.
- Oncogenes induce genotoxic stress by mitotic processing of unusual replication intermediates
- Genomic instability — an evolving hallmark of cancer
- ERCC1 and MUS81–EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis
- Cotranscriptionally formed DNA:RNA hybrids mediate transcription elongation impairment and transcription-associated recombination.
- Genome-organizing factors Top2 and Hmo1 prevent chromosome fragility at sites of S phase transcription.
- RNase H2-Initiated Ribonucleotide Excision Repair
- Double-Strand Break Repair Independent Role For BRCA2 In Blocking Stalled Replication Fork Degradation By MRE11
- Mechanisms of trinucleotide repeat instability during human development
- The MRE11 complex: starting from the ends
- Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability.
- Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway
- R loops: from transcription byproducts to threats to genome stability.
- Increased replication initiation and conflicts with transcription underlie Cyclin E-induced replication stress
- Transcription-replication encounters, consequences and genomic instability
- Common Fragile Site Tumor Suppressor Genes and Corresponding Mouse Models of Cancer
- Replication Stress and Mechanisms of CNV Formation
- Common fragile sites: mechanisms of instability revisited.
- Two Distinct Modes of ATR Activation Orchestrated by Rad17 and Nbs1
- Common fragile site profiling in epithelial and erythroid cells reveals that most recurrent cancer deletions lie in fragile sites hosting large genes.
Cited by
- Enhancer of Rudimentary Homolog Affects the Replication Stress Response through Regulation of RNA Processing
- ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA
- HIV-1 Vpr degrades the HLTF DNA translocase in T cells and macrophages
- Trial Watch: Targeting ATM–CHK2 and ATR–CHK1 pathways for anticancer therapy
- Distinct functions of human RecQ helicases during DNA replication.
- The importance of an interaction network for proper DNA polymerase ζ heterotetramer activity
- Emerging roles of CST in maintaining genome stability and human disease
- SAMHD1 acts at stalled replication forks to prevent interferon induction
- SAMHD1 and the innate immune response to cytosolic DNA during DNA replication.
- Mechanistic insights into the multiple activities of the Rad5 family of enzymes.
- INVESTIGATING CHECKPOINT KINASES 1/2 AS NOVEL THERAPEUTIC TARGETS IN HEAD AND NECK SQUAMOUS CELL CARCINOMA
- USP7 is essential for maintaining Rad18 stability and DNA damage tolerance
- Ku Stabilizes Replication Forks in the Absence of Brc1
- Cancer therapy and replication stress: forks on the road to perdition.
- Rôle de la protéine Cdk5 en réponse aux dommages de l’ADN : implications dans les points de contrôle S et G2/M
- LAMMER kinase contributes to genome stability in Ustilago maydis
- An investigation into the function of the SUMOylation of Nse2 and PCNA in S. pombe
- PTEN Regulates DNA Replication Progression and Stalled Fork Recovery
- The Epigenetic Regulators ATRX and CTCF are Required for Mouse Neuroprogenitor Cell Survival and Brain Development
- Binding of Multiple Rap1 Proteins Stimulates Chromosome Breakage Induction during DNA Replication
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