MicroRNAs as Biomarkers in Cancer
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Summary
The prospect of miRNAs as potential diagnostic and prognostic biomarkers with clinical applications is significant as more evidence points to their central role in cancer pathobiology.
- Type
- review
- Published
- 2013-01-16
- Cited by
- 41
- References
- 119
- Access
- Open access
- OpenAlex
- https://openalex.org/W2038920886
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:5465308
Keywords
microRNA, Computational biology, Biomarker, Cancer biomarkers, Diagnostic biomarker
References
- High expression of serum miR-17-5p associated with poor prognosis in patients with hepatocellular carcinoma.
- Hodgkin lymphoma cell lines are characterized by a specific miRNA expression profile.
- MicroRNA-34b/c suppresses uveal melanoma cell proliferation and migration through multiple targets
- Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs
- The 3′ untranslated region of messenger RNA: A molecular ‘hotspot’ for pathology?
- MicroRNA expression profiling in prostate cancer.
- Endogenous human microRNAs that suppress breast cancer metastasis
- Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer.
- Identification of novel microRNA targets based on microRNA signatures in bladder cancer
- Serum miR-210 as a novel biomarker for molecular diagnosis of clear cell renal cell carcinoma.
- MicroRNA signatures differentiate melanoma subtypes
- MicroRNAs in cell proliferation, cell death, and tumorigenesis
- Causes and Consequences of microRNA Dysregulation
- Combination of plasma microRNAs with serum CA19‐9 for early detection of pancreatic cancer
- Elevated expression of microRNAs 155, 203, 210 and 222 in pancreatic tumors is associated with poorer survival
- Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells.
- Haemolysis during Sample Preparation Alters microRNA Content of Plasma
- MicroRNA expression profiling of thyroid tumors: biological significance and diagnostic utility.
- Profiling and Functional Analyses of MicroRNAs and Their Target Gene Products in Human Uterine Leiomyomas
- A microRNA Imparts Robustness Against Environmental Fluctuation During Development
Cited by
- Genome-wide analysis of DNA methylation in bovine placentas
- Availability of Circulating MicroRNAs as a Biomarker for Early Diagnosis of Diffuse Large B-Cell Lymphoma
- Quantifying Expression and Loss of MiRNA in CLL B Cells and Plasma, and Modeling DEP Separation of B Cells, Plasma, and RNA From Blood
- Novel approaches toward managing the micromanagers: ‘non-toxic’ but effective
- Detection of miRNA using a surface plasmon resonance biosensor and antibody amplification
- A study of inflammatory cytokine gene polymorphisms in B-cell diseases
- Ultrasensitive SPR detection of miRNA‐93 using antibody‐enhanced and enzymatic signal amplification
- MiRNA-210: A Current Overview.
- Characterisation and validation of Mel38; A multi-tissue microRNA signature of cutaneous melanoma
- Rare-earth-doped upconversion nanocrystals embedded mesoporous silica nanoparticles for multiple microRNA detection
- MicroRNA-Based Biomarkers in the Diagnosis and Monitoring of Therapeutic Response in Patients with Depression
- Higher levels of TNF and IL‐4 cytokines and low miR‐182 expression in visceral leishmaniasis‐HIV co‐infected patients
- Radiation-induced circulating miRNA expression in blood of head and neck cancer patients
- Genetic biomarkers: Potential roles in cancer diagnosis.
- Circulating miR-16-5p, miR-92a-3p, and miR-451a in Plasma from Lung Cancer Patients: Potential Application in Early Detection and a Regulatory Role in Tumorigenesis Pathways
- Multifunctional Roles of miR-34a in Cancer: A Review with the Emphasis on Head and Neck Squamous Cell Carcinoma and Thyroid Cancer with Clinical Implications
- Circulating miRNAs in HER2-Positive and Triple Negative Breast Cancers: Potential Biomarkers and Therapeutic Targets
- The Role of MicroRNAs in the Progression, Prognostication, and Treatment of Breast Cancer
- The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer's disease pathology: from antioxidant to epigenetic therapy.
- Translation of a circulating melanoma microRNA profile into a solid tissue assay to improve diagnostic accuracy
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