Levodopa and the progression of Parkinson's disease.

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Summary

The clinical data suggest that levodopa either slows the progression of Parkinson's disease or has a prolonged effect on the symptoms of the disease, and the neuroimaging data suggest either thatlevodopa accelerates the loss of nigrostriatal dopamine nerve terminals or that its pharmacologic effects modify the dopamine transporter.

Type
article
Published
2004-12-09
Cited by
1,828
References
32
Access
Open access

Keywords

Levodopa, Medicine, Parkinsonism, Placebo, Carbidopa

References

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