A lymphotoxin-beta-specific receptor.
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Summary
A receptor specific for human LT-beta was identified, which suggests that cell surface LT may have functions that are distinct from those of secreted LT-alpha.
- Type
- letter
- Published
- 1994-04-29
- Cited by
- 407
- References
- 37
- OpenAlex
- https://openalex.org/W2030829559
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11635763
Keywords
Lymphotoxin, Lymphotoxin alpha, Lymphotoxin beta receptor, Receptor, Tumor necrosis factor alpha
References
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- Studies on the differing effects of tumor necrosis factor and lymphotoxin on the growth of several human tumor lines.
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- Lymphotoxin and an associated 33-kDa glycoprotein are expressed on the surface of an activated human T cell hybridoma.
- Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity.
- A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen.
- Expression of surface lymphotoxin and tumor necrosis factor on activated T, B, and natural killer cells.
- Lymphotoxin is expressed as a heteromeric complex with a distinct 33-kDa glycoprotein on the surface of an activated human T cell hybridoma.
- The structure of human lymphotoxin (tumor necrosis factor-beta) at 1.9-A resolution.
- The structure of tumor necrosis factor-alpha at 2.6 A resolution. Implications for receptor binding.
- A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins.
- Production of lymphotoxin (LT alpha) and a soluble dimeric form of its receptor using the baculovirus expression system.
- CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM
- Biochemical characterization of the extracellular domain of the 75-kilodalton tumor necrosis factor receptor.
- Complementary DNA cloning of a receptor for tumor necrosis factor and demonstration of a shed form of the receptor.
- Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes.
- Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection.
- A novel domain within the 55 kd TNF receptor signals cell death.
- Structure of tumour necrosis factor
Cited by
- Tumour necrosis factors in immune regulation: everything that's interesting is...new!
- Vaccinia virus strains Lister, USSR and Evans express soluble and cell-surface tumour necrosis factor receptors.
- Expression of lymphotoxins and their receptor-Fc fusion proteins by baculovirus.
- Gene transfer of Fc-fusion cytokine by in vivo electroporation: application to gene therapy for viral myocarditis
- Protein therapeutics targeted at the TNF superfamily.
- Increased plasma LIGHT levels in patients with atopic dermatitis
- Molecular and cellular mechanisms of T lymphocyte apoptosis.
- Review: Death Domain Receptors and Their Role in Cell Demise
- Comparative Characterization of Lymphotoxin Transcripts from Human B- and T-Cell Lines, Peripheral Lymphocytes, and Normal Tissues
- The ligands and receptors of the lymphotoxin system.
- Prions and the immune system: A trip through intestine, spleen, lymph nodes and nerves
- Microanatomy and Function of the Spleen
- Physiological, Immunological, and Pathological Functions of Tumor Necrosis Factor (TNF) Revealed by TNF Receptor-Deficient Mice
- Fas and Fas ligand: a death factor and its receptor.
- The role of tumor necrosis factor and lymphotoxin in lymphoid organ development.
- Receptors for hematopoietic regulatory cytokines: overview of structure and function.
- Regulation of Early T Cell Activation by TNF Superfamily Members TNF and FASL: A Dissertation
- Regulation of cell fate by lymphotoxin (LT) receptor signalling: Functional differences and similarities of the LT system to other TNF superfamily (TNFSF) members.
- Risiko von Infektionen unter einer Behandlung mit Tumornekrosefaktor-α-Inhibitoren
- The role of DcR3 in systemic lupus erythematosus and islet β-Cell viability and function
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