Molecular and cellular mechanisms of T lymphocyte apoptosis.
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Summary
This chapter focuses on the genetic and molecular mechanisms of T lymphocyte apoptosis and also deals with the various phases of apoptosis initiation, execution, and degradation of lymphocytes.
- Type
- review
- Published
- 1998-01-01
- Cited by
- 81
- References
- 576
- OpenAlex
- https://openalex.org/W25044289
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:39912654
Keywords
Biology, Cell biology, Apoptosis, Lymphokine, Programmed cell death
References
- Transmission of signals from the T lymphocyte antigen receptor to the genes responsible for cell proliferation and immune function: the missing link.
- Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35.
- Rescue of signaling by a chimeric protein containing the cytoplasmic domain of CD45.
- Activation of Raf by ionizing radiation
- Calcium-dependent, Interleukin 1β-converting Enzyme Inhibitor-insensitive Degradation of Lamin B1 and DNA Fragmentation in Isolated Thymocyte Nuclei*
- Antiapoptotic signalling by the insulin-like growth factor I receptor, phosphatidylinositol 3-kinase, and Akt
- Development and selection of T cells: facts and puzzles.
- Involvement of p21ras distinguishes positive and negative selection in thymocytes.
- MLK‐3 activates the SAPK/JNK and p38/RK pathways via SEK1 and MKK3/6.
- Cross‐linking CD40 on B cells preferentially induces stress‐activated protein kinases rather than mitogen‐activated protein kinases.
- The cell death inhibitor Bcl‐2 and its homologues influence control of cell cycle entry.
- Bcl-2 blocks loss of mitochondrial membrane potential while ICE inhibitors act at a different step during inhibition of death induced by respiratory chain inhibitors.
- Bcl‐2 mutants with restricted subcellular location reveal spatially distinct pathways for apoptosis in different cell types.
- CD30 ligand is frequently expressed in human hematopoietic malignancies of myeloid and lymphoid origin.
- CD95 (APO-1/Fas) induces activation of SAP kinases downstream of ICE-like proteases.
- Phosphatidylserine externalization is a downstream event of interleukin-1 beta-converting enzyme family protease activation during apoptosis.
- Thapsigargin induces mitochondrial dysfunction and apoptosis in the mastocytoma P815 cell line and in mouse thymocytes.
- HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway.
- Compartmentalization of the peripheral immune system.
- Interleukin-2, autotolerance, and autoimmunity.
Cited by
- Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Signaling in Activated T Cells Abrogates TRAIL-Induced Apoptosis Upstream of the Mitochondrial Amplification Loop and Caspase-81
- Pml is essential for multiple apoptotic pathways
- Control of apoptotic DNA degradation
- Further Differentiation of Murine Double-Positive Thymocytes Is Inhibited in Adenosine Deaminase-Deficient Murine Fetal Thymic Organ Culture1
- Lysophosphatidic acid and sphingosine 1-phosphate protection of T cells from apoptosis in association with suppression of Bax.
- The role of calcium in apoptosis
- Increased apoptosis of peripheral blood T cells following allogeneic hematopoietic cell transplantation.
- Role of the Passive Apoptotic Pathway in Graft-Versus-Host Disease1
- RXR- and RAR-selective retinoids in psoriasis and (pre)malignant skin disorders
- Immune response against dying tumor cells.
- Specific Inhibition of Glucocorticoid-Induced Thymocyte Apoptosis by Substance P1
- Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signaling
- Autonomic innervation of immune organs and neuroimmune modulation.
- The Role of c-FLIP in Modulation of CD95-induced Apoptosis*
- Microarray analysis of spaceflown murine thymus tissue reveals changes in gene expression regulating stress and glucocorticoid receptors
- The central role of the mitochondrial megachannel in apoptosis: evidence obtained with intact cells, isolated mitochondria, and purified protein complexes.
- La mitochondrie, chef d'orchestre de la mort cellulaire
- Characterization of Apt- cell lines exhibiting cross-resistance to glucocorticoid- and Fas-mediated apoptosis
- Derivatives of monoglycerides as apoptotic agents in T-cells
- Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy
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