Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes.
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Summary
A previously undescribed adhesion molecule, VCAM-1, which is induced by cytokines on human endothelial cells and binds lymphocytes is cloned using a novel method requiring neither monoclonal antibodies nor purified protein.
- Type
- article
- Published
- 1989-12-22
- Cited by
- 1,740
- References
- 45
- OpenAlex
- https://openalex.org/W2001720727
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:44396168
Keywords
Biology, Jurkat cells, VCAM-1, Cell adhesion molecule, Molecular biology
References
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- ICAM, an adhesion ligand of LFA-1, is homologous to the neural cell adhesion molecule NCAM
- Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families.
- A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.
- De novo expression of intercellular-adhesion molecule 1 in melanoma correlates with increased risk of metastasis.
- Functional cloning of ICAM-2, a cell adhesion ligand for LFA-1 homologous to ICAM-1
- Molecular cloning of a cDNA coding biliary glycoprotein I: primary structure of a glycoprotein immunologically crossreactive with carcinoembryonic antigen.
- Rapid and sensitive protein similarity searches.
Cited by
- VLA‐4 integrin on sarcoma cell lines recognizes endothelial VCAM‐1. Differential regulation of the VLA‐4 avidity on various sarcoma cell lines
- Vascular cell adhesion molecule-1 and eosinophil adhesion to cultured human umbilical vein endothelial cells in vitro.
- Mast Cell Progenitor Trafficking in Allergic Airway Inflammation
- Analysis of monocyte chemoattractant protein 1-mediated lung injury using rat lung organ cultures.
- Tumour necrosis factor alpha is pro‐inflammatory in normal human skin and modulates cutaneous adhesion molecule expression
- Cytokine-mediated tumor-endothelial cell interaction in metastasis.
- Oncogenes and expression of endogenous lectins and glycoconjugates
- Tumor necrosis factor decreases thrombin receptor expression in endothelial cells
- Identification of the binding site in intercellular adhesion molecule 1 for its receptor, leukocyte function-associated antigen 1.
- Cell adhesion molecules and cancer metastasis.
- Up-regulation of circulating adhesion molecules in bronchiectasis.
- Vascular Cell Adhesion Molecule-1 Augments Adenovirus-Mediated Gene Transfer
- Expressions of ICAM-1 and its mRNA in sera and tissues of patients with hepatocellular carcinoma.
- Vascular cell adhesion molecule‐1 (VCAM‐1) blockade in collagen‐induced arthritis reduces joint involvement and alters B cell trafficking
- Leukocyte migration and adhesion.
- Acute effect of cigarette smoke on TNF-alpha release by macrophages mediated through the erk1/2 pathway.
- Adhesion and signaling molecules controlling the transmigration of leukocytes through endothelium
- [The role of adhesion molecules in cutaneous inflammation].
- Histologic analysis of an immune response in the lung parenchyma of mice. Angiopathy accompanies inflammatory cell influx.
- Inhibition of colon carcinoma cell lung colony formation by a soluble form of E-selectin.
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