Creatine metabolism and the urea cycle.
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Summary
It is clear that patients with urea cycle disorders also have altered creatine metabolism, and there is some evidence that this may decrease brain creatine levels which may contribute to the neurological symptoms exhibited by these patients.
- Type
- article
- Published
- 2010-01-01
- Cited by
- 117
- References
- 30
- OpenAlex
- https://openalex.org/W2029775581
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:26363489
Keywords
Creatine, Arginine, Urea cycle, Urea, Creatinine
References
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- Apoprotein A-V: An important regulator of triglyceride metabolism
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- Guanidino compounds in plasma, urine and cerebrospinal fluid of hyperargininemic patients during therapy.
- Distinctly abnormal brain metabolism in late-onset ornithine transcarbamylase deficiency
- High cerebral guanidinoacetate and variable creatine concentrations in argininosuccinate synthetase and lyase deficiency: implications for treatment?
- Guanidinoacetate and creatine/creatinine levels in controls and patients with urea cycle defects.
- Clinical, biochemical, and molecular spectrum of hyperargininemia due to arginase I deficiency
- Arginine, an indispensable amino acid for patients with inborn errors of urea synthesis.
- Exocytotic release of creatine in rat brain
- Inhibition of tumor necrosis factor‐induced apoptosis in transgenic mouse liver expressing creatine kinase
Cited by
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- Proteomic Analysis of Human Brown Adipose Tissue Reveals Utilization of Coupled and Uncoupled Energy Expenditure Pathways
- Optimisation pharmacologique des dérivés de la créatine pour le traitement du déficit en transporteur de la créatine
- Multimodal magnetic resonance investigation of childhood metabolic neurodegenerative disease
- Transport of Amino Acids in the Kidney
- Identificación de la mutación y317x del gen slc6a8 y su posible asociación con retraso mental y epilepsia en usuarios del hospital psiquiátrico Dr. Samuel Ramírez moreno
- NMR metabolic profiling of serum identifies amino acid disturbances in chronic fatigue syndrome.
- Physiological responses of Australian Merino wethers exposed to high heat load.
- The role of creatine in the organism of pigs and its effect on the quality of pork: a review / Rola kreatyny w organizmie świń i jej wpływ na jakość mięsa wieprzowego: artykuł przeglądowy
- Following healthy pregnancy by nuclear magnetic resonance (NMR) metabolic profiling of human urine.
- Growth, body characteristics and blood parameters of ostrich chickens receiving commercial probiotics
- Maternal creatine homeostasis is altered during gestation in the spiny mouse: is this a metabolic adaptation to pregnancy?
- Hyperargininemia: 7-month follow-up under sodium benzoate therapy in an Italian child presenting progressive spastic paraparesis, cognitive decline, and novel mutation in ARG1 gene.
- Everolimus and Sirolimus in Combination with Cyclosporine Have Different Effects on Renal Metabolism in the Rat
- D-Arginine as a neuroprotective amino acid: promising outcomes for neurological diseases.
- Ammonia toxicity to the brain
- Dietary requirements of “nutritionally non-essential amino acids” by animals and humans
- The metabolic burden of creatine synthesis
- Encapsulation of teniposide into albumin nanoparticles with greatly lowered toxicity and enhanced antitumor activity.
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