Inhibition of rat liver arginase by an intermediate in NO biosynthesis, NG-hydroxy-L-arginine: implications for the regulation of nitric oxide biosynthesis by arginase.
Explore this paper's citation graph
Summary
NG-hydroxy-L-arginine, an intermediate in the biosynthesis of nitric oxide (NO), has been found to be a uniquely potent competitive inhibitor of rat liver arginase, which may have significant implications for the regulation of NO levels in tissues or cells, such as liver or macrophages.
- Type
- article
- Published
- 1994-07-15
- Cited by
- 175
- References
- 0
- OpenAlex
- https://openalex.org/W2011992952
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11144549
Keywords
Arginase, Arginine, Biosynthesis, Nitric oxide, Biochemistry
References
No references recorded for this paper.
Cited by
- Regulation of L-arginine transport and metabolism in vascular smooth muscle cells
- Macrophages, Oscillators And Fish: Using Dynamical Systems To Examine Biological Problems
- Nitric oxide, an iceberg in cardiovascular physiology: far beyond vessel tone control.
- Radical aspects on arthritis : the role of neutrophil generation of nitric oxide and superoxide in inflammatory conditions
- Chemistry of N-hydroxy-L-arginine.
- Macrophage polarisation: immune responses of carp against parasites
- Purification of a Multipotent Antideath Activity from Bovine Liver and Its Identification as Arginase: Nitric Oxide-Independent Inhibition of Neuronal Apoptosis
- Effect of Cinnamomum cassia methanol extract and sildenafil on arginase and sexual function of young male Wistar rats.
- rIFN-γ-mediated growth suppression of platinum-sensitive and -resistant ovarian tumor cell lines not dependent upon arginase inhibition
- Metabolism of agmatine in macrophages: modulation by lipopolysaccharide and inhibitory cytokines.
- Arginine: beyond protein.
- Inhibitor coordination interactions in the binuclear manganese cluster of arginase.
- Binding of the unreactive substrate analog L-2-amino-3-guanidinopropionic acid (dinor-L-arginine) to human arginase I.
- Mechanisms involved in the effect of nitric oxide synthase inhibition on L‐arginine‐induced insulin secretion
- Experimental studies of OH° radical/pressure dependence of arginase activity using a molecular chromatography approach.
- Polyamines inhibit lipopolysaccharide-induced nitric oxide synthase activity in rat liver cytosol.
- Effects of the new arginase inhibitor N(omega)-hydroxy-nor-L-arginine on NO synthase activity in murine macrophages.
- Autoantibody to the liver arginase present in sera of patients with autoimmune hepatitis and chronic hepatitis.
- Reduction of N(ω)-hydroxy-L-arginine by the mitochondrial amidoxime reducing component (mARC).
- N-Hydroxyguanidines oxidation by a N3S copper-complex mimicking the reactivity of Dopamine beta-Hydroxylase.
Related papers
- Increased serum arginase activity in depressed patients.
- Arginine uptake by chick kidney mitochondria.
- l-Arginine deprivation impairs Leishmania major-specific T-cell responses
- Kidney arginase activity in chicks fed diets containing deficient or excessive concentrations of lysine, arginine, histidine, or total nitrogen.
- Arginine metabolism in cyanobacteriumAnabaena cycadeae: Regulation of arginine uptake and arginase by ammonia
- Studies on the advent of ureotelism. Factors that render the hepatic arginase of the Mexican axolotl able to hydrolyse endogenous arginine.
- Arginine metabolism in the blood cells of cattle and goats.