Cancer epigenomics: DNA methylomes and histone-modification maps
Explore this paper's citation graph
Summary
It is time to 'upgrade' cancer epigenetics research and put together an ambitious plan to tackle the many unanswered questions in this field using epigenomics approaches.
- Type
- review
- Published
- 2007-04-01
- Cited by
- 2,215
- References
- 113
- OpenAlex
- https://openalex.org/W2029197798
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4801662
Keywords
Epigenomics, Biology, Epigenetics, DNA methylation, Histone
References
- The Consensus Coding Sequences of Human Breast and Colorectal Cancers
- Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
- Beyond the double helix: writing and reading the histone code.
- A gene hypermethylation profile of human cancer.
- Early detection: The power and the promise of DNA methylation markers
- Fingerprinting genomes using PCR with arbitrary primers.
- Evidence for an instructive mechanism of de novo methylation in cancer cells
- High sensitivity mapping of methylated cytosines.
- Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis.
- A bivalent chromatin structure marks key developmental genes in embryonic stem cells.
- A blueprint for a Human Epigenome Project: the AACR Human Epigenome Workshop.
- Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
- Loss of imprinting of IGF2: a common epigenetic modifier of intestinal tumor risk.
- A profile of methyl-CpG binding domain protein occupancy of hypermethylated promoter CpG islands of tumor suppressor genes in human cancer.
- Cancer-testis antigens: promising targets for antigen directed antineoplastic immunotherapy
- DNA Methylation Profiling of the Human Major Histocompatibility Complex: A Pilot Study for the Human Epigenome Project
- Myc represses transcription through recruitment of DNA methyltransferase corepressor
- Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors
- Human DNA Methyltransferase 1 Is Required for Maintenance of the Histone H3 Modification Pattern*
- Methyl CpG‐binding proteins and transcriptional repression *
Cited by
- Biological signature of HER2-positive breast cancer
- Effects of DNA Methyltransferase- and Histone Deacetylase Inhibitors on ALK Positive Anaplastic Large Cell Lymphoma
- Cancer Epigenetics
- Centromeres in cell division, evolution, nuclear organization and disease
- A microRNA DNA methylation signature for human cancer metastasis
- Computational methods for identification of recurrent copy number alteration patterns by array CGH
- Visualization of DNA methylation and histone modifications in living cells.
- High-Resolution Melting Analysis of BLU Methylation Levels in Gastric, Colorectal, and Pancreatic Cancers
- Methylation patterns of genes coding for drug-metabolizing enzymes in tamoxifen-resistant breast cancer tissues
- Epigenomics and ovarian carcinoma
- TERRA: Long Noncoding RNA at Eukaryotic Telomeres.
- [Technological advances in single-cell genomic analyses].
- The tumor suppressor role of CTCF
- A proposed framework for assessing risk from less-than-lifetime exposures to carcinogens
- Epigenetics: Principles and Practice
- Epigenetic mechanisms and cancer: An interface between the environment and the genome
- Expression of glioma stem cell marker CD133 and O6-methylguanine-DNA methyltransferase is associated with resistance to radiotherapy in gliomas.
- Emerging promise of epigenetics and DNA methylation for the diagnosis and management of women's cancers.
- Tumor Heterogeneity: Mechanisms and Bases for a Reliable Application of Molecular Marker Design
- Polycomb and DNA methyltransferase complexes participate in global and focal epigenetic alteration in cancer cells.
Related papers
- Functional Analysis of Promoter CPG-Methylation using a CpG-Free Luciferase Reporter Vector
- Methylation of CpG dinucleotides in the open reading frame of a testicular germ cell-specific intronless gene, Tact1/Actl7b, represses its expression in somatic cells.
- Detection of aberrant methylation of the p15INK4B gene promoter.
- Dry and Wet Studies on the DNA Methylation and Transcription Factor Binding Sites of the Promotor Region of ASPP2 Gene
- Effect of DNA methylation on dynamic properties of the helix and nuclear protein binding in the H-ras promoter.
- Quantitative Analysis of p73 Gene Promoter Methylation
- CpG and Non-CpG Methylation in Epigenetic Gene Regulation and Brain Function
- Early demethylation of non-CpG, CpC-rich, elements in the myogenin 5’-flanking region
- Effects of CpG Methylation on Recognition of DNA by the Tumour Suppressor p53
- DNA Methylation-Dependent Epigenetic Regulation of Gene Expression in MCF-7 Breast Cancer Cells