Antihypertensive drugs in very old people: a subgroup meta-analysis of randomised controlled trials. INDANA Group.
Explore this paper's citation graph
Summary
Results of a large-scale specific trial are needed for definite conclusion that antihypertensive treatment is beneficial in very elderly hypertensive patients, as an age threshold beyond which hypertension should not be treated cannot be justified.
- Type
- review
- Published
- 1999-03-06
- Cited by
- 647
- References
- 25
- OpenAlex
- https://openalex.org/W2027805815
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:43858004
Keywords
Subgroup analysis, Meta-analysis, Medicine, Randomized controlled trial, MEDLINE
References
- New meta-analysis of treatment trials of hypertension: improving the estimate of therapeutic benefit.
- INDANA: a meta-analysis on individual patient data in hypertension. Protocol and preliminary results.
- Influence of antihypertensive drug treatment on morbidity and mortality in patients over the age of 60 years. European Working Party on High blood pressure in the Elderly (EWPHE) results: sub-group analysis on entry stratification.
- Hypertensive Cardiovascular Disease: Pathophysiology and Treatment
- Influence of antihypertensive drug treatment on morbidity and mortality in patients over the age of 60 years. EWPHE results: subgroup analysis based on entry stratification
- Considerations for the meta-analysis of randomized clinical trials. Summary of a panel discussion.
- A Health-Status Index and its Application to Health-Services Outcomes
- Blood pressure reduction in elderly: a randomised controlled trial of methyldopa.
- Effect of two different therapeutic approaches on total and cardiovascular mortality in a Cardiovascular Study in the Elderly (CASTEL).
- Randomised trial of treatment of hypertension in elderly patients in primary care.
- Hypertension in the Elderly Implications and Generalizability of Randomized Trials
- Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension *
- Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension)
- Prospective study on the treatment of mild hypertension in the aged.
- Morbidity and mortality in the Systolic Hypertension in the Elderly Program (SHEP) pilot study.
- MORTALITY AND MORBIDITY RESULTS FROM THE EUROPEAN WORKING PARTY ON HIGH BLOOD PRESSURE IN THE ELDERLY TRIAL
- A general parametric approach to the meta-analysis of randomized clinical trials.
- Antihypertensive drug therapy in the elderly
- The Australian therapeutic trial in mild hypertension.
- The Hypertension in the Very Elderly Trial (HYVET).
Cited by
- Treatment of hypertension in the elderly.
- Applicability to primary care of national clinical guidelines on blood pressure lowering for people with stroke: cross sectional study
- Intramuscular gluteal injections in the increasingly obese population: retrospective study
- Besonderheiten der Pharmakotherapie beim älteren Hypertoniker
- Hypertension strategies in the third millennium: conservatism, evidence and the folly of speculation
- ACCF/AHA 2011 expert consensus document on hypertension in the elderly: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents.
- Dietary fats and dietary cholesterol and risk of stroke in women.
- Patient experiences of adverse drug reactions
- Effect Modification of Interventions. Bridging the Gap Between Clinical Studies and the Individual Patient
- Blutdruck und Gehirn
- Hypertension – diagnostic and therapeutic differencies in the elderly
- L’hypertension artérielle chez le sujet âgé : prise en charge thérapeutique en intégrant les dernières recommandations européennes et nord-américaines
- Association between measures of and prognostic significance of cardiorespiratory fitness in community-dwelling older adults
- The elderly patients on hemodialysis
- Guidelines for management of ischaemic stroke and transient ischaemic attack 2008.
- Nonagenarians in internal medicine: characteristics, outcomes and predictors for in-hospital and post-discharge mortality.
- 資料 老年者高血圧治療ガイドライン--2002年改訂版--厚生労働省長寿科学総合研究班
- Preface: evidence-based practice guideline for the treatment of chronic kidney disease
- Hypertension and Stroke
- An investigation of the influence of a European formulary on general practitioner prescribing as part of an educational intervention
Related papers
- Empirical comparison of subgroup effects in conventional and individual patient data meta-analyses
- Meta-analysis of the changes of peripheral blood regulatory T cell to CD4+ T cell ratio in patients with systemic sclerosis
- The polymorphism (Gln261Arg) of 12-lipoxygenase and cancer risk: a meta-analysis.
- Homocysteine (HCY) levels in patients with atrial fibrillation (AF): A meta‐analysis
- [Application of Meta-regression and subgroup analyses of heterogeneity disposal in Meta-analysis].
- Epstein-Barr virus infection and oral squamous cell carcinoma risk: A meta-analysis
- Comparing the Overall Result and Interaction in Aggregate Data Meta-Analysis and Individual Patient Data Meta-Analysis
- Serum/Plasma Zinc Is Apparently Increased in Ischemic Stroke: a Meta-analysis
- PAI-1 4G/4G Genotype Is Associated with Recurrent Implantation Failure: a Systematic Review and Meta-analysis
- Success rate of sialendoscopy. A systematic review and meta-analysis.