Hypertension in the Elderly Implications and Generalizability of Randomized Trials
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Summary
Randomized trials demonstrate that treating healthy older persons with hypertension is highly efficacious, and five-year morbidity and mortality benefits derived from trials are greater for older than younger subjects.
- Type
- article
- Published
- 1994-12-28
- Cited by
- 53
- References
- 40
- OpenAlex
- https://openalex.org/W2072425740
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:265992416
Keywords
Medicine, Clinical trial, Population, Confidence interval, Disease
References
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- Blood pressure reduction in elderly: a randomised controlled trial of methyldopa.
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- Systolic Hypertension in the Elderly Program (SHEP): antihypertensive efficacy of chlorthalidone.
- Randomised trial of treatment of hypertension in elderly patients in primary care.
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- Introduction: is hypertension a metabolic disease?
- Effects of treatment in hypertension. Results of a controlled study.
- Systolic hypertension in the elderly. Pathophysiology and management.
- Systolic Hypertension in the Elderly: An Epidemiologic Assessment
- Echocardiographically detected left ventricular hypertrophy: prevalence and risk factors. The Framingham Heart Study.
- Management of multiple risk factors for coronary heart disease in patients with hypertension.
- Blood Pressure Management: Individualized Treatment Based on Absolute Risk and the Potential for Benefit
Cited by
- Effect of antihypertensive treatment in patients having already suffered from stroke. Gathering the evidence. The INDANA (INdividual Data ANalysis of Antihypertensive intervention trials) Project Collaborators.
- Antihypertensive therapy. Angiotensin-converting enzyme inhibitors, angiotensin II receptor antagonists, and calcium antagonists.
- Health outcomes associated with antihypertensive therapies used as first-line agents. A systematic review and meta-analysis.
- Guidelines for managing raised blood pressure
- Kardiovaskuläre Pharmakotherapie im Alter
- Health outcomes associated with various antihypertensive therapies used as first-line agents: a network meta-analysis.
- Using Numerical Results from Systematic Reviews in Clinical Practice
- Cardiovascular risk management of hypertension and hypercholesterolaemia in the Netherlands: from unifactorial to multifactorial approach
- Antihypertensive drugs in very old people: a subgroup meta-analysis of randomised controlled trials. INDANA Group.
- Hypertension in older adults.
- Opportunity cost
- Has the use of angiotensin converting enzyme inhibitors and calcium channel blockers improved the outcome for hypertensive patients?
- The number needed to treat: a useful clinical measure or a case of the Emperor's new clothes?
- A Large Scale Study of Angiotensin II Inhibition Therapy in an Elderly Population: the Chance Study
- Long‐Term Survival and Use of Antihypertensive Medications in Older Persons
- Systematic review of randomised controlled trials of multiple risk factor interventions for preventing coronary heart disease
- Update of Diuretics in the Treatment of Hypertension
- Paradoxical Relations of Drug Treatment with Mortality in Older Persons
- Systematic review of antihypertensive therapies: does the evidence assist in choosing a first-line drug?
- Comprehensive Geriatric Assessment (CGA) in general practice: Results from a pilot study in Vorarlberg, Austria
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