The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription
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Summary
The results indicate that active and inactive rRNA genes can be demarcated by their associated proteins, and link chromatin remodeling to DNA methylation and specific histone modifications.
- Type
- article
- Published
- 2002-11-01
- Cited by
- 447
- References
- 27
- OpenAlex
- https://openalex.org/W2027047074
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:27291652
Keywords
Biology, Chromatin remodeling, Histone methylation, Genetics, DNA methylation
References
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- The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase Gcn5p
- Two different chromatin structures coexist in ribosomal RNA genes throughout the cell cycle.
- The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription
- The many faces of chromatin remodeling: SWItching beyond transcription.
- Molecular mechanisms mediating methylation-dependent silencing of ribosomal gene transcription.
- A family of chromatin remodeling factors related to Williams syndrome transcription factor.
- Targeting histone deacetylase complexes via KRAB-zinc finger proteins: the PHD and bromodomains of KAP-1 form a cooperative unit that recruits a novel isoform of the Mi-2alpha subunit of NuRD.
- The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p.
- ACF consists of two subunits, Acf1 and ISWI, that function cooperatively in the ATP-dependent catalysis of chromatin assembly.
- Widespread Collaboration of Isw2 and Sin3-Rpd3 Chromatin Remodeling Complexes in Transcriptional Repression
Cited by
- Nucleolar dysfunction may be associated with infertility in humans.
- Hypermethylation of 18S and 28S Ribosomal DNAs Predicts Progression-Free Survival in Patients with Ovarian Cancer
- Proinsulin C-peptide Regulates Ribosomal RNA Expression*
- Die Verteilung transkribierender RNA-Polymerase I auf ribosomaler DNA
- Reduced rRNA expression and increased rDNA promoter methylation in CD34+ cells of patients with myelodysplastic syndromes.
- Molecular basis for the autonomous promotion of cell proliferation by angiogenin
- Expansion of the ISWI chromatin remodeler family with new active complexes
- Comparative genetic analysis of the 45S rDNA intergenic spacers from three Saccharum species
- TbISWI and its role in transcriptional control in Trypanosoma brucei
- Chromatin Remodeling by BRG1 and SNF2H : Biochemistry and Function
- Nuclear architecture and structural dynamics - molecular basis of chromatin remodeling induced by human ISWI machines -
- Nucleolus: the ribosome factory.
- Functional analysis of ISWI complexes in mammalian cells.
- ADN ribosomique 5S chez Arabidopsis thaliana : dynamique chromatinienne et ARN polymérase IV
- Molecular mechanisms of nucleosome positioning and DNA methylation in chromatin
- DNA methylation in chromatin - complexes and mechanisms
- Searching for active ribosomal genes.
- Genetic and Molecular Characterization of ISWI Family Chromatin Remodelers in Wingless Signaling.
- Chromatin remodeling factors and DNA replication.
- The histone H3K9 methylation and RNAi pathways regulate normalnucleolar and repeated DNA organization by inhibiting formation ofextrachromosomal DNAs
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