Hypermethylation of 18S and 28S Ribosomal DNAs Predicts Progression-Free Survival in Patients with Ovarian Cancer
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Summary
In ovarian cancer cell lines, methylation levels of rDNA correlated with gene down-regulation and 5′-aza-2′-deoxycytidine treatment resulted in a moderate increase in 18S and 28S rDNA gene expressions.
- Type
- article
- Published
- 2005-10-15
- Cited by
- 70
- References
- 30
- Access
- Open access
- OpenAlex
- https://openalex.org/W16243810
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:15643207
Keywords
Humanities, Philosophy, Computer science, Mathematics
References
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Cited by
- Epigenomics and ovarian carcinoma
- Epigenetic markers of ovarian cancer.
- Emerging promise of epigenetics and DNA methylation for the diagnosis and management of women's cancers.
- Epigenetics in ovarian cancer.
- Nuclear envelope alterations generate an aging‐like epigenetic pattern in mice deficient in Zmpste24 metalloprotease
- DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcome-predicting and treatment-implicating study
- Identification of endogenous reference genes for qRT-PCR analysis in normal matched breast tumor tissues.
- MicroRNA-135b promotes lung cancer metastasis by regulating multiple targets in the Hippo pathway and LZTS1
- TGF-β: friend or foe? The role of TGF-β/SMAD signaling in epigenetic silencing of ovarian cancer and its implication in epigenetic therapy
- Genetic and epigenetic changes of genes on chromosome 3 in human urogenital tumors
- FT-IR Microspectrometry Reveals the Variation of Membrane Polarizability due to Epigenomic Effect on Epithelial Ovarian Cancer
- Role of ERCC1 promoter hypermethylation in drug resistance to cisplatin in human gliomas
- Translational Application of Epigenetic Alterations: Ovarian Cancer as a Model
- Epigenetic silencing of ARNTL, a circadian gene and potential tumor suppressor in ovarian cancer.
- Promoter hypermethylation of FBXO32, a novel TGF-β/SMAD4 target gene and tumor suppressor, is associated with poor prognosis in human ovarian cancer
- CRABP1-reduced expression is associated with poorer prognosis in serous and clear cell ovarian adenocarcinoma
- RNA polymerases I and III, non-coding RNAs and cancer.
- TRIM56 Is a Virus- and Interferon-Inducible E3 Ubiquitin Ligase That Restricts Pestivirus Infection
- The role of UBF in regulating the structure and dynamics of transcriptionally active rDNA chromatin
- Comprehensive methylome analysis of ovarian tumors reveals hedgehog signaling pathway regulators as prognostic DNA methylation biomarkers
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