Depletion of intracellular calcium stores activates a calcium current in mast cells
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Summary
Combined patch-clamp and Fura-2 measurements are combined to monitor membrane currents in mast cells under conditions where intracellular Ca2+ stores were emptied by either inositol 1,4,5-trisphosphate, ionomycin, or excess of theCa2+ chelator EGTA to identify a sustained calcium inward current that is not voltage-activated and shows a characteristic inward rectification.
- Type
- article
- Published
- 1992-01-23
- Cited by
- 1,790
- References
- 25
- OpenAlex
- https://openalex.org/W2015480034
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4372392
Keywords
Ionomycin, Calcium, Intracellular, Biophysics, Chemistry
References
- Inositol trisphosphate isomers, but not inositol 1,3,4,5-tetrakisphosphate, induce calcium influx in Xenopus laevis oocytes.
- Receptor-operated calcium influx in rat hepatocytes. Identification and characterization using manganese.
- Rat liver peroxisomes catalyze the beta oxidation of fatty acids.
- Refill status of the agonist-sensitive Ca2+ pool regulates Mn2+ influx into parotid acini.
- Relationship of thyrotropin-releasing hormone-induced spike and plateau phases in cytosolic free Ca2+ concentrations to hormone secretion. Selective blockade using ionomycin and nifedipine.
- Receptor-mediated calcium entry in fura-2-loaded human platelets stimulated with ADP and thrombin. Dual-wavelengths studies with Mn2+.
- Characterization of ionomycin as a calcium ionophore.
- Heparin inhibits the inositol 1,4,5‐trisphosphate‐induced Ca2+ release from rat liver microsomes
- Inositol phosphates and cell signalling
- Second messenger‐activated calcium influx in rat peritoneal mast cells.
- Agonist‐stimulated divalent cation entry into single cultured human umbilical vein endothelial cells.
- Chloride conductance activated by external agonists and internal messengers in rat peritoneal mast cells.
- Mitogen-induced oscillations of cytosolic Ca2+ and transmembrane Ca2+ current in human leukemic T cells.
- Activation of Ca2+ entry into acinar cells by a non-phosphorylatable inositol trisphosphate
- Exchange characteristics of the noradrenaline‐sensitive calcium store in vascular smooth muscle cells or rabbit ear artery.
- Synergism of inositol trisphosphate and tetrakisphosphate in activating Ca2+-dependent K+ channels
- Regulation of calcium influx by second messengers in rat mast cells
- The initiation of calcium release following muscarinic stimulation in rat lacrimal glands.
- Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.
- Inactivation of Ca channels.
Cited by
- Stored calcium modulates inositol phosphate synthesis in cultured smooth muscle cells.
- The role of the intracellular signaling pathway in Ehrlichia canis infection in vitro
- Calcium signaling in mast cells: focusing on L-type calcium channels.
- [Ca2+]i oscillations in sympathetic neurons: an experimental test of a theoretical model.
- Depletion of InsP3 stores activates a Ca2+ and K+ current by means of a phosphatase and a diffusible messenger
- Calcium-dependent potentiation of store-operated calcium channels in T lymphocytes
- Extracellular site for econazole‐mediated block of Ca2+ release‐activated Ca2+ current (Icrac) in T lymphocytes
- Inhibition of antigen-induced acute bronchoconstriction, airway hyperresponsiveness, and mast cell degranulation by a nonanticoagulant heparin: comparison with a low molecular weight heparin.
- Store depletion and calcium influx.
- Slow Feedback Inhibition of Calcium Release-activated Calcium Current by Calcium Entry*
- Interactions between Ca2+ and cAMP in ecdysteroid secretion from the prothoracic glands of Bombyx mori.
- Capacitative Ca2+ entry is graded with degree of intracellular Ca2+ store depletion in bovine vascular endothelial cells
- CaT1 manifests the pore properties of the calcium-release-activated calcium channel
- Human T-cell lymphotropic virus type 1 p12(I) expression increases cytoplasmic calcium to enhance the activation of nuclear factor of activated T cells.
- Capacitative calcium entry in the nervous system.
- Expresión diferencial de canales de calcio en células normales y tumorales de colon humano
- Effects of prolactin on ionic membrane conductances in the human malignant astrocytoma cell line U87-MG.
- The intracellular dissipation of cytosolic calcium following glucose re‐addition to carbohydrate depleted Saccharomyces cerevisiae
- Two‐photon analysis of calcium signals in T lymphocytes of intact lamina propria from human intestine
- Arachidonate‐regulated Ca2+‐selective (ARC) channel activity is modulated by phosphorylation and involves an A‐kinase anchoring protein
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