Current evidence for the clinical use of long-chain polyunsaturated N-3 fatty acids to prevent age-related cognitive decline and Alzheimer's disease
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Summary
A practical overview and rating of the level and type of available evidence that n-3 LC-PUFA supplements are safe and protective against cognitive aging and Alzheimer’s disease is provided, with additional discussion of the evidence for effects on quality of life, vascular aging, and the rate of aging.
- Type
- article
- Published
- 2013-02-19
- Cited by
- 73
- References
- 156
- Access
- Open access
- OpenAlex
- https://openalex.org/W2015142237
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23548988
Keywords
Polyunsaturated fatty acid, Cognitive decline, Dementia, Disease, Medicine
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- A controlled trial
Cited by
- Nutraceuticals in cognitive impairment and Alzheimer’s disease
- FATTY ACIDS AND MERCURY IN SEVENTY SEVEN SPECIES OF COMMERCIALLY AVAILABLE FINFISH IN THE UNITED STATES
- Efficient Docosahexaenoic Acid Uptake by the Brain from a Structured Phospholipid
- Nutrition and brain aging: how can we move ahead?
- Lack of Dietary Polyunsaturated Fatty Acids Causes Synapse Dysfunction in the Drosophila Visual System
- Human Cerebrospinal Fluid Fatty Acid Levels Differ between Supernatant Fluid and Brain-Derived Nanoparticle Fractions, and Are Altered in Alzheimer's Disease
- Current evidence for the use of coffee and caffeine to prevent age-related cognitive decline and Alzheimer's disease
- Docosahexaenoic Acid and Adult Memory: A Systematic Review and Meta-Analysis
- Omega-3 fatty acids regulate the interaction of the Alzheimer's aβ(25-35) peptide with lipid membranes.
- Dual effect of docosahexaenoic acid (attenuation or amplification) on C22:0-, C24:0-, and C26:0-Induced mitochondrial dysfunctions and oxidative stress on human neuronal SK-N-BE cells
- Serum polyunsaturated fatty acid composition and serum high-sensitivity C-reactive protein levels in healthy Japanese residents: The KOBE study
- Modulation des lipides du cerveau par l’alimentation : études chez des modèles animaux de maladies neurodégénératives
- n-3 LCPUFA improves cognition: the young, the old and the sick.
- Dysregulation of Soluble Epoxide Hydrolase and Lipidomic Profiles in Anorexia Nervosa
- Nutrient biomarkers and vascular risk factors in subtypes of mild cognitive impairment: A cross-sectional study
- Omega-3 fatty acids and stress-induced changes to mood and cognition in healthy individuals.
- MAPT STUDY: A MULTIDOMAIN APPROACH FOR PREVENTING ALZHEIMER’S DISEASE: DESIGN AND BASELINE DATA
- Omega-3 Fatty Acid Status Enhances the Prevention of Cognitive Decline by B Vitamins in Mild Cognitive Impairment
- Fatty acids and mineral composition of melon (Cucumis melo L. Inodorus) seeds from West Algeria
- Dietary DHA supplementation causes selective changes in phospholipids from different brain regions in both wild type mice and the Tg2576 mouse model of Alzheimer's disease
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