MacroH2A1 isoforms are associated with epigenetic markers for activation of lipogenic genes in fat‐induced steatosis
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Summary
This study shows that the macroH2A1 isoforms play an important role in the regulation of lipid accumulation in hepatocytes and underlines the importance of the replacement of noncanonical histones in theregulation of genes involved in lipid metabolism in the progression of steatosis
- Type
- article
- Published
- 2015-05-01
- Cited by
- 43
- References
- 43
- Access
- Open access
- OpenAlex
- https://openalex.org/W2013660990
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9926715
Keywords
H3K4me3, Chromatin immunoprecipitation, Epigenetics, Biology, Steatosis
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Cited by
- Mitoguardin Regulates Mitochondrial Fusion through MitoPLD and Is Required for Neuronal Homeostasis.
- DNA Hypomethylation and Histone Variant macroH2A1 Synergistically Attenuate Chemotherapy-Induced Senescence to Promote Hepatocellular Carcinoma Progression
- The Histone Variant MacroH2A1.2 is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1
- Persistent Chromatin Modifications Induced by High Fat Diet*♦
- QKI5-mediated alternative splicing of the histone variant macroH2A1 regulates gastric carcinogenesis
- NeuCode proteomics reveals Bap1 regulation of metabolism
- Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma
- Telomerase reverse transcriptase (TERT) ‐ enhancer of zeste homolog 2 (EZH2) network regulates lipid metabolism and DNA damage responses in glioblastoma
- MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD+ consumption
- Histone MacroH2A1: A Chromatin Point of Intersection between Fasting, Senescence and Cellular Regeneration
- The MacroH2A1.1 – PARP1 Axis at the Intersection Between Stress Response and Metabolism
- Senolytic Cocktail Dasatinib+Quercetin (D+Q) Does Not Enhance the Efficacy of Senescence-Inducing Chemotherapy in Liver Cancer
- Macro Histone Variants: Emerging Rheostats of Gastrointestinal Cancers
- The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs
- Isolation of senescent cells by iodixanol (OptiPrep) density gradient‐based separation
- MIGA2 Links Mitochondria, the ER, and Lipid Droplets and Promotes De Novo Lipogenesis in Adipocytes.
- The histone variant macroH2A1.1 regulates RNA Polymerase II paused genes within defined chromatin interaction landscapes
- The taming of PARP1 and its impact on NAD+ metabolism
- Tethering Fat: Tethers in Lipid Droplet Contact Sites
- Epigenetics factors in nonalcoholic fatty liver disease
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