Differential expression of orexin receptors 1 and 2 in the rat brain
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Summary
The differential distribution of oxin receptors is consistent with the proposed multifaceted roles of orexin in regulating homeostasis and may explain the unique role of the OX2R receptor in regulating sleep state stability.
- Type
- article
- Published
- 2001-06-18
- Cited by
- 1,641
- References
- 46
- OpenAlex
- https://openalex.org/W2013655437
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24692229
Keywords
Dorsal raphe nucleus, Orexin, Orexin receptor, Biology, Neuroscience
References
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- Hypothalamic Arousal Regions Are Activated during Modafinil-Induced Wakefulness
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- Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system
- Orexin A activates locus coeruleus cell firing and increases arousal in the rat.
Cited by
- Orexins (hypocretins) directly excite tuberomammillary neurons
- Induction of active (REM) sleep and motor inhibition by hypocretin in the nucleus pontis oralis of the cat.
- Orexins and their receptors: structural aspects and role in peripheral tissues
- Roles of orexins in the regulation of feeding and arousal.
- Neuropeptide Y Y1 receptor mRNA in rodent brain: Distribution and colocalization with melanocortin‐4 receptor
- Schizophrenia, hypocretin (orexin), and the thalamocortical activating system.
- Orphan G-Protein-Coupled Receptors
- Hypocretin-2 Saporin Lesions of the Ventrolateral Periaquaductal Gray (vlPAG) Increase REM Sleep in Hypocretin Knockout Mice
- Hypocretin1/OrexinA axon targeting of laterodorsal tegmental nucleus neurons projecting to the rat medial prefrontal cortex.
- Orexin/Hypocretin Activates mTOR Complex 1 (mTORC1) via an Erk/Akt-independent and Calcium-stimulated Lysosome v-ATPase Pathway*
- Hypocretin/orexin antagonism enhances sleep-related adenosine and GABA neurotransmission in rat basal forebrain
- Orexin Receptor Antagonism Improves Sleep and Reduces Seizures in Kcna1-null Mice.
- Association of orexin receptor polymorphisms with antipsychotic-induced weight gain
- Emerging role of orexin antagonists in insomnia therapeutics: An update on SORAs and DORAs
- Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors
- Locus Coeruleus and Tuberomammillary Nuclei Ablations Attenuate Hypocretin/Orexin Antagonist-Mediated REM Sleep123
- Hypocretinergic system in the medial preoptic area promotes maternal behavior in lactating rats.
- Nucleus accumbens dopamine receptors mediate hypothalamus‐induced antinociception in the rat formalin test
- Orexin 2 receptor stimulation enhances resilience, while orexin 2 inhibition promotes susceptibility, to social stress, anxiety and depression
- Sexual Reward and Depression
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