Schizophrenia, hypocretin (orexin), and the thalamocortical activating system.
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Summary
Evidence for an underlying loss of excitatory thalamocortical connectivity in schizophrenia is taken together with evidence that stress in this illness could further exacerbate a breakdown in cortical processing of incoming information from the ascending arousal system.
- Type
- article
- Published
- 2006-10-27
- Cited by
- 63
- References
- 48
- Access
- Open access
- OpenAlex
- https://openalex.org/W17656637
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:17243943
Keywords
Political science
References
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- The hypocretins: Setting the arousal threshold
Cited by
- Thalamic‐insular dysconnectivity in schizophrenia: Evidence from structural equation modeling
- Directional Indicator on Neural Oscillations as a Measure of Synaptic Plasticity in Chronic Unpredictable Stress Rats
- Localization of prolyl oligopeptidase in the thalamic and cortical projection neurons: a retrograde neurotracing study in the rat brain.
- Serotonin-2C and -2A Receptor Co-expression on Cells in the Rat Medial Prefrontal Cortex
- Post weaning social isolation influences spatial cognition, prefrontal cortical synaptic plasticity and hippocampal potassium ion channels in Wistar rats.
- Hypocretin mechanisms in nicotine addiction: evidence and speculation
- The nonspecific thalamus: A place in a wedding bed for making memories last?
- Dominant rats are natural risk takers and display increased motivation for food reward.
- The Hypocretin System and Psychiatric Disorders
- Orexins/hypocretins and aminergic systems
- Systemic and intrabasalis administration of the orexin-1 receptor antagonist, SB-334867, disrupts attentional performance in rats
- The reuniens and rhomboid nuclei: Neuroanatomy, electrophysiological characteristics and behavioral implications
- Orexin/hypocretin modulation of the basal forebrain cholinergic system: role in attention
- Psychosis in Patients with Narcolepsy as an Adverse Effect of Sodium Oxybate
- Tobacco Addiction and the Dysregulation of Brain Stress Systems
- Structural and functional alterations to rat medial prefrontal cortex following chronic restraint stress and recovery
- Hypocretin (Orexin) Regulates Glutamate Input to Fast-Spiking Interneurons in Layer V of the Fr2 Region of the Murine Prefrontal Cortex
- Directionality index of neural information flow as a measure of synaptic plasticity in chronic unpredictable stress rats.
- Role of lateral hypothalamus in two aspects of attention in associative learning
- fMRI Assessment of Thalamocortical Connectivity during Attentional Performance
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