Positive selection of antigen-specific T cells in thymus by restricting MHC molecules

Keywords

T-cell receptor, MHC restriction, Major histocompatibility complex, CD8, MHC class I

References

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• Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cellsHung Sia Teh, Paweł Kisielow, Bernadette Scott — 1988
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• Fine specificity of a continuously growing killer cell clone specific for H‐Y antigenHarald von Boehmer, Hans Hengartner, Markus Nabholz — 1979

Cited by

• Allelic exclusion at DNA rearrangement level is required to prevent coexpression of two distinct T cell receptor beta genesShara D Sohn — 1991
• Increased frequency of T cell receptor V alpha 12.1 expression on CD8+ T cells: evidence that V alpha participates in shaping the peripheral T cell repertoire [published erratum appears in J Exp Med 1991 Nov 1;174(5):following 1286]Hama Arba Diallo — 1991
• Self-nonself discrimination by T cells.Harald von Boehmer, Paweł Kisielow — 1990
• The role of nuclear position and locus conformation in regulating V(D)J recombination of the Tcrb locusRyan Schlimgen — 2008
• Mechanisms underlying the formation of the T cell receptor repertoire in rheumatoid arthritis.Osmo Nikkilä — 1995
• The Action of Bax and Bcl-2 on T Cell SelectionYanosuke Ôtuka — 1998
• Crucial function of the pre‐T‐cell receptor (TCR) in TCRP selection, TCRβ allelic exclusion and αβ versus γδ lineage commitmentSunil Kumar, B. K. Choubey — 1998
• αβTCR+ Cells Are a Minimal Fraction of Peripheral CD8+ Pool in MHC Class I-Deficient Mice1José Luis de Castro Ruano — 2000
• Positive selection of a Qa-1-restricted T cell receptor with specificity for insulin.D Putri Syarfita — 2002
• Development and selection of T cells: facts and puzzles.Paweł Kisielow, Harald von Boehmer — 1995
• Endogenous galectin‐1 enforces class I‐restricted TCR functional fate decisions in thymocytesLuís Millones Figueroa — 2008
• Positive and negative selection in BaselM. Ahyerre, M. Chabanel, N. Aires — 2008
• Positive-selection-inducing self-peptides displayed by cortical thymic epithelial cells.Julie Villanova — 2015
• Treatment of an Autoimmune Disease with “Classical” T Cell Veto: A ProposalUwe D. Staerz, Yan Qi — 1999
• Functional studies of candidate genes contributing to type 1 diabetes in the NOD mouseMarie Lundholm — 2009
• Identification of a novel thymocyte growth factor derived from B cell lymphomas.Takashi Suda, Ian A. MacNeil, Melissa A. Fischer — 1991
• Development and function of thymocyte-selected CD4 T cellsYu Qiao — 2010
• The interdisciplinary science of T-cell recognition.Johannes B. Huppa, Mark M. Davis — 2013
• The effect of maternal thymus on the behavior of T cells in mice progeny after exposure to Benzo(a)pyrene during pregnancyGodwin O. Wolisi — 1996
• T cell tolerance and antigen presenting cell function in the thymus.David J. Izon, John D. Nieland, Lori Jones — 1993

Related papers

• Antigen presentation by MHC class II moleculesSarah M. Weenink, Anand M. Gautam — 1997
• Principles of MHC class I-mediated antigen presentation and T cell selection.Hans‐Gustaf Ljunggren, Christopher J. Thorpe — 1996
• Interleukin-10 down-regulates MHC class II alphabeta peptide complexes at the plasma membrane of monocytes by affecting arrival and recycling.Bruce Koppelman, Jacques Neefjes, J E de Vries — 1997
• MHC class II restricted antigen presentation.Jean Pieters — 1997
• Intracellular transport of MHC class II molecules.Jacques Neefjes, Hidde L. Ploegh — 1992
• Peptide loading onto recycling HLA‐DR molecules occurs in early endosomesValérie Pinet, Eric O. Long — 1998
• Expression of invariant chain can cause an allele-dependent increase in the surface expression of MHC class I moleculesA. Reber, Hēth Turnquist, Heather J. Thomas — 2002
• Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men.Tjadine M. Holling, Erik van Schooten, Peter J. van den Elsen — 2004
• Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentationRoger Belizaire, Emil R. Unanue — 2009