Functional studies of candidate genes contributing to type 1 diabetes in the NOD mouse
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Summary
The non-obese diabetic mouse is one of the best and most commonly studied animal models for T1D and can be used as a surrogate for type 1 diabetes patients for both genetic and environmental factors.
- Type
- article
- Published
- 2009-01-01
- Cited by
- 0
- References
- 342
- Access
- Open access
- OpenAlex
- https://openalex.org/W49323012
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:80913534
Keywords
Nod, Type 1 diabetes, NOD mice, Gene, Diabetes mellitus
References
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- Assessing the role of HLA-linked and unlinked determinants of disease.
- The mucosal milieu creates tolerogenic dendritic cells and TR1 and TH3 regulatory cells
- Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Iβ
- The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
- Checkpoint blockade in cancer immunotherapy.
- The B7–CD28 superfamily
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- Two Autoimmune Diabetes Loci Influencing T Cell Apoptosis Control Susceptibility to Experimental Autoimmune Myocarditis1
- Control of autoimmunity by naturally arising regulatory CD4+ T cells.
- Cutting edge: lymphoproliferative disease in the absence of CTLA-4 is not T cell autonomous.
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