MiRNA Expression May Account for Chronic but Not for Acute Regulation of mRNA Expression in Human Thyroid Tumor Models
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Summary
Analysis of miRNA and mRNA expressions profiles in the cell lines has shown that they have evolved into a common, dedifferentiated phenotype, closer to ATC than to the tumors they are derived from, suggesting that they represent a useful model for undifferentiated thyroid cancer.
- Type
- article
- Published
- 2014-11-06
- Cited by
- 8
- References
- 32
- Access
- Open access
- OpenAlex
- https://openalex.org/W2013432316
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:18235873
Keywords
microRNA, Messenger RNA, Carcinogenesis, Cell culture, Thyroid
References
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Cited by
- 2-Iodohexadecanal inhibits thyroid cell growth in part through the induction of let-7f microRNA.
- microRNA expression in autonomous thyroid adenomas: Correlation with mRNA regulation.
- Association between microRNA polymorphisms and papillary thyroid cancer susceptibility.
- miRNA expression and function in thyroid carcinomas: a comparative and critical analysis and a model for other cancers
- Thyroid follicular adenomas and carcinomas: molecular profiling provides evidence for a continuous evolution
- Long noncoding RNA NEAT1 regulate papillary thyroid cancer progression by modulating miR‐129‐5p/KLK7 expression
- Long noncoding RNA LINC00313 modulates papillary thyroid cancer tumorigenesis via sponging miR-4429.
- miR-146a rs2910164 Polymorphism and Risk of Papillary Thyroid Carcinoma: A Meta-Analysis
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