MiRNA Expression May Account for Chronic but Not for Acute Regulation of mRNA Expression in Human Thyroid Tumor Models

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Summary

Analysis of miRNA and mRNA expressions profiles in the cell lines has shown that they have evolved into a common, dedifferentiated phenotype, closer to ATC than to the tumors they are derived from, suggesting that they represent a useful model for undifferentiated thyroid cancer.

Type
article
Published
2014-11-06
Cited by
8
References
32
Access
Open access

Keywords

microRNA, Messenger RNA, Carcinogenesis, Cell culture, Thyroid

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