Generation of somatic sensory neuron diversity and implications on sensory coding
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Summary
How intrinsic transcription factors interface with target-derived signals to specify these functionally distinct sensory neurons is discussed and how this control mechanism provides a developmental perspective for the coding of somatic sensations is discussed.
- Type
- review
- Published
- 2010-10-01
- Cited by
- 122
- References
- 50
- Access
- Open access
- OpenAlex
- https://openalex.org/W2013411637
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13327328
Keywords
Neuroscience, Sensory system, Nociceptor, Stimulus modality, Dorsal root ganglion
References
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Cited by
- Parcellation of Cblns 1, 2, and 4 among different subpopulations of dorsal horn neurons in mouse spinal cord
- Role of TLx3 in the development of the somatosensory system
- Molecular, genetic, cellular, and network functions in the spinal cord and brainstem
- Dependence on the transcription factor Shox2 for specification of sensory neurons conveying discriminative touch
- Modulation of sensory function by high glucose-induced oxidative stress: Role of TRPV1 receptors
- Defining neurochemical properties and functions of primary sensory neurons in the rat trigeminal ganglion
- Cannabidiol stimulates Aml‐1a‐dependent glial differentiation and inhibits glioma stem‐like cells proliferation by inducing autophagy in a TRPV2‐dependent manner
- DEVELOPMENT AND FUNCTIONS OF C-LOW-THRESHOLD MECHANORECEPTORS
- The role of miR-146a in dorsal root ganglia neurons of experimental diabetic peripheral neuropathy
- The transcription factor Cux2 marks development of an A-delta sublineage of TrkA sensory neurons.
- TNFα/TNFR1 signaling is required for the development and function of primary nociceptors
- c-Maf Is Required for the Development of Dorsal Horn Laminae III/IV Neurons and Mechanoreceptive DRG Axon Projections
- A multifunctional neurotrophin with reduced affinity to p75NTR enhances transplanted Schwann cell survival and axon growth after spinal cord injury.
- New insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms?
- The fundamental unit of pain is the cell
- The Transcription Factor c-Maf Controls Touch Receptor Development and Function
- Oxidative stress induces itch via activation of transient receptor potential subtype ankyrin 1 (TRPA1) in mice
- Nerve endings reveal hidden diversity in the skin
- Peripheral pain-sensing neurons: from molecular diversity to functional specialization.
- Molecular interactions underlying the specification of sensory neurons.
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