Altered signalling and gene expression associated with the immune system and the inflammatory response in obesity
Explore this paper's citation graph
Summary
The present paper will focus on the molecular mechanisms linking obesity and inflammation with emphasis on the alteration of signalling and gene expression in adipose cell components.
- Type
- review
- Published
- 2007-10-01
- Cited by
- 133
- References
- 37
- Access
- Open access
- OpenAlex
- https://openalex.org/W2013369999
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:39999348
Keywords
Adipose tissue, Adipokine, Adipose tissue macrophages, White adipose tissue, Inflammation
References
- Diet, Nutrition, and the Prevention of Chronic Diseases
- PI3K delta and PI3K gamma: partners in crime in inflammation in rheumatoid arthritis and beyond?
- Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells.
- Visfatin, an Adipocytokine with Proinflammatory and Immunomodulating Properties
- Paracrine interactions of mammalian adipose tissue.
- Microarray profiling of isolated abdominal subcutaneous adipocytes from obese vs non-obese Pima Indians: increased expression of inflammation-related genes
- Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.
- Atrial natriuretic peptide inhibits the production of adipokines and cytokines linked to inflammation and insulin resistance in human subcutaneous adipose tissue
- Emerging role of cathepsin S in obesity and its associated diseases
- Relationship between adipocyte size and adipokine expression and secretion.
- Inflammation and metabolic disorders
- Acquired obesity increases CD68 and tumor necrosis factor-alpha and decreases adiponectin gene expression in adipose tissue: a study in monozygotic twins.
- Obesity is associated with macrophage accumulation in adipose tissue.
- Increased expression of inflammation-related genes in cultured preadipocytes/stromal vascular cells from obese compared with non-obese Pima Indians
- Adiponectin gene expression and adipocyte NF-κB transcriptional activity in elderly overweight and obese women: inter-relationships with fat distribution, hs-CRP, leptin and insulin resistance
- Human visfatin expression: relationship to insulin sensitivity, intramyocellular lipids, and inflammation.
- Adiponectin, the missing link in insulin resistance and obesity.
- Adiponectin inhibits LPS-induced NF-κB activation and IL-6 production and increases PPARγ2 expression in adipocytes
- Monocyte chemoattractant protein-1 in subcutaneous abdominal adipose tissue: characterization of interstitial concentration and regulation of gene expression by insulin.
- Inflammatory Gene Expression Patterns Revealed by DNA Microarray Analysis in TNF-α-treated SGBS Human Adipocytes
Cited by
- Dietary fat and the prevention of type 2 diabetes: impact on inflammation and underlying mechanisms
- Etude des adipokines en relation avec le syndrome métabolique et l'inflammation
- Relationship of centrally-located body fat to appetitive hormones in healthy postmenopausal women
- Effects of Bojungchiseub-tang on the Production of Inflammatory Adipokine and MAPK Signaling in 3T3-L1 Mature Adipocytes
- Classical monocytes from patients with pancreatic ductal adenocarcinoma exhibit a significantly altered transcriptome profile compared with healthy volunteers
- Associação de poliformismos de genes relacionados à obesidade e comorbidades com resposta à intervenção no estilo de vida de indivíduos de risco cardiometabólico
- The cell size and distribution of adipocytes from subcutaneous and visceral fat is associated with type 2 diabetes mellitus in humans
- Atividade da via do mTOR no músculo esquelético da prole é afetada pelo consumo materno de dieta hiperlipídica e difere entre os animais neonatos e lactentes
- Análisis de polimorfismos de genes asociados al síndrome metabólico en niños obesos
- Studies of the interaction between diabetes family history, exercise, adiposity and metabolic health
- EFEITOS COMPORTAMENTAIS E BIOQUÍMICOS DA DIETA INTERMITENTE NA VIGÊNCIA DE UM ESTÍMULO INFLAMATÓRIO NO HIPOCAMPO DE RATOS
- Cloning Changes the Response to Obesity of Innate Immune Factors in Blood, Liver, and Adipose Tissues in Domestic Pigs
- SCD1 mediates the influence of exogenous saturated and monounsaturated fatty acids in adipocytes: Effects on cellular stress, inflammatory markers and fatty acid elongation.
- Obesidad y sedentarismo en el siglo XXI: ¿qué se puede y se debe hacer?
- Expression of Innate Immune Response Genes in Liver and Three Types of Adipose Tissue in Cloned Pigs
- The periodontal disease-systemic health-infectious disease axis in developing countries.
- Elucidating the roles of stearoyl-CoA desaturase 1 in adipocyte fatty acid metabolism and cellular function.
- 2-Benzamido-N-(1H-benzo[d]imidazol-2-yl)thiazole-4-carboxamide derivatives as potent inhibitors of CK1δ/ε
- Effects of feeding fish oil on mesenteric lymph node cytokine responses in obese leptin receptor-deficient JCR:LA-cp rats
- Grape powder extract attenuates tumor necrosis factor α-mediated inflammation and insulin resistance in primary cultures of human adipocytes.
Related papers
- [Adipocytokines and assay method in metabolic syndrome].
- Characteristics of Adiponectin and Coronary Plaque – An Intravascular Ultrasound Study
- Circulating anti-inflammatory adipokines High Molecular Weight Adiponectin and Zinc-α2-glycoprotein (ZAG) are inhibited in early sepsis, but increase with clinical recovery: a pilot study
- Are leptin and adiponectin involved in recurrent pregnancy loss?
- Review on Adiponectin: A Benevolent Adipokine
- A Review of the Potential Preventive Effects of Adiponectin in Major Cancers
- Adiponectin in health and disease
- ADIPOKINES AND NONALCOHOLIC FATTY LIVER DISEASE
- Progress in Effects of Adiponectin on Cardiovascular System
- Association between Adipokines and Biomarkers of Alzheimer’s Disease: A Cross-Sectional Study