Inflammatory sites as a source of plasma neopterin: measurement of high levels of neopterin and markers of oxidative stress in pus drained from human abscesses.
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Summary
The concentration of total neopterin suggests that 7,8-dihydroneopterin could act as an antioxidant during inflammation, suggesting plasma neopter in originates from inflammatory sites.
- Type
- article
- Published
- 2008-09-01
- Cited by
- 30
- References
- 46
- OpenAlex
- https://openalex.org/W2012425435
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:25256790
Keywords
Neopterin, Oxidative stress, Antioxidant, Chemistry, Inflammation
References
- Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque.
- Separation of pteridines from blood cells and plasma by reverse-phase high-performance liquid chromatography.
- Dityrosine and tyrosine oxidation products are endogenous markers for the selective proteolysis of oxidatively modified red blood cell hemoglobin by (the 19 S) proteasome.
- Potential to inhibit growth of atherosclerotic plaque development through modulation of macrophage neopterin/7,8‐dihydroneopterin synthesis
- Reactive species and their accumulation on radical-damaged proteins.
- Protection of U937 cells from free radical damage by the macrophage synthesized antioxidant 7,8-dihydroneopterin
- Induction of apoptosis in human blood T cells by 7,8-dihydroneopterin: the difference between healthy controls and patients with systemic lupus erythematosus.
- Protein Hydroperoxides are a Major Product of Low Density Lipoprotein Oxidation During Copper, Peroxyl Radical and Macrophage-mediated Oxidation
- Moderate hyperhomocysteinaemia and immune activation in patients with rheumatoid arthritis.
- Formation of oxygen radicals in solutions of 7,8-dihydroneopterin.
- Serum Protein-Bound 3,4-Dihydroxyphenylalanine and Related Products of Protein Oxidation and Chronic Hemodialysis
- Inhibition of protein oxidation by the macrophage-synthesised antioxidant 7,8-dihydroneopterin
- Effect of neopterin and 7,8‐dihydroneopterin on tumor necrosis factor‐α induced programmed cell death
- Dissociation of neopterin and 7,8-dihydroneopterin from plasma components before HPLC analysis.
- Inhibition of THP-1 cell-mediated low-density lipoprotein oxidation by the macrophage-synthesised pterin, 7,8-dihydroneopterin
- Lipid oxidation predominates over protein hydroperoxide formation in human monocyte-derived macrophages exposed to aqueous peroxyl radicals
- A comparative evaluation of thiobarbituric acid methods for the determination of malondialdehyde in biological materials.
- Inhibition of monocyte luminol‐dependent chemiluminescence by tetrahydrobiopterin, and the free radical oxidation of tetrahydrobiopterin, dihydrobiopterin and dihydroneopterin
- Neopterin Blood Levels: A Basis for Deciding to Use Antibiotics in Intensive Care Unit (ICU) Patients
- Pteridine derivatives as modulators of oxidative stress.
Cited by
- Inhibition of macrophage metabolism by oxLDL
- Oxidised low density lipoprotein causes human macrophage cell death through oxidant generation and inhibition of key catabolic enzymes.
- Research Report 2008
- Intracellular glutathione protects human monocyte-derived macrophages from hypochlorite damage.
- Neopterin suppresses the activity of tryptophan-degrading enzyme indoleamine 2,3-dioxygenase in human peripheral blood mononuclear cells
- Pathogenic Role of Macrophages in Intradermal Infection of Methicillin-Resistant Staphylococcus aureus in Thermally Injured Mice
- Association of plasma B-6 vitamers with systemic markers of inflammation before and after pyridoxine treatment in patients with stable angina pectoris.
- Potential use of sFlt-1 and pterin to predict the clinical outcome of cardiovascular disease.
- Mechanisms of 7,8-dihydroneopterin protection of macrophages from cytotoxicity
- Identification of dityrosine cross-linked sites in oxidized human serum albumin.
- A model of complex plaque formation: 7,8-Dihydroneopterin protects human monocyte-derived macrophages from oxidised low density lipoprotein-induced death
- Pathogenic role of macrophages in intradermal infection of methicillin-resistant Staphylococcus aureus in thermally injured mice
- Neopterin and 7,8-dihydroneopterin are generated within atherosclerotic plaques
- Repetitive cryotherapy attenuates the in vitro and in vivo mononuclear cell activation response
- A quantitative structure—property relationship (QSPR) study of singlet oxygen generation by pteridines
- Thiol oxidation and di-tyrosine formation in human plasma proteins induced by inflammatory concentrations of hypochlorous acid.
- Cognitive ability in Down Syndrome and its relationship to urinary neopterin, a marker of activated cellular immunity
- The effect of 1 week of repeated ischaemic leg preconditioning on simulated Keirin cycling performance: a randomised trial
- Neopterin, Inflammation, and Oxidative Stress: What Could We Be Missing?
- Theoretical study of photoreactions between oxidized pterins and molecular oxygen
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