The effect of fasting on tissue cyclic cAMP and plasma glucagon in the obese hyperglycemic mouse.
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Summary
The +/+ mice exhibited an increase in cAMP levels in skeletal muscle, fat and liver with fasting, while the ob/ob mice had increased levels of cAMP in fat, but not in muscle and had a paradoxical decrease in liver cAMP Levels with fasting.
- Type
- article
- Published
- 1975-09-01
- Cited by
- 41
- References
- 0
- Access
- Open access
- OpenAlex
- https://openalex.org/W1966504330
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:34307122
Keywords
Internal medicine, Endocrinology, Glycogenolysis, Glucagon, Stimulation
References
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Cited by
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- Secretion of insulin and glucagon by the perfused pancreas of genetically obese (fa/fa) Zucker rats and its alteration with aging.
- Lipolysis and cyclic AMP levels in epididymal adipose tissue of obese-hyperglycaemic mice
- Effects of dibutyryl adenosine 3',5'-monophosphate on hepatic metabolism of free fatty acids.
- Kinetic and functional characterization of 1,4-dideoxy-1, 4-imino-d-arabinitol: a potent inhibitor of glycogen phosphorylase with anti-hyperglyceamic effect in ob/ob mice.
- Increased dose-response relationship of liver plasma membrane adenylate cyclase to glucagon stimulation in diabetic rats. A possible role of the guanyl nucleotide-binding regulatory protein
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- Decrease of glutathione and induction of gamma-glutamyltransferase by dibutyryl-3', 5'-cyclic AMP in rat liver.
- The gastro-entero-pancreatic hormone response to fasting in obesity
- Effect of starvation on hepatic glycogen metabolism and glucose homeostasis.
- Increased concentration of fructose 2,6‐bisphosphate in livers of genetically obese mice
- Insulin and Glucagon: Plasma Levels and Pancreatic Release in the Genetically Obese Zucker Rat
- Effects of Oxaloacetate and β-Hydroxybutyrate on Rat Liver Mitochondrial Calcium Flow during Starvation
- Laboratory animals exhibiting obesity and diabetes syndromes.
- Immunoreactive Glucagon Levels in Obese-hyperglycemic (ob/ob) Mice
- Hepatic amino acid-degrading enzyme expression is downregulated by natural and synthetic ligands of PPARα in rats.
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