A new antibiotic kills pathogens without detectable resistance
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Summary
The properties of this compound suggest a path towards developing antibiotics that are likely to avoid development of resistance, as well as several methods to grow uncultured organisms by cultivation in situ or by using specific growth factors.
- Type
- article
- Published
- 2015-01-07
- Cited by
- 2,316
- References
- 56
- Access
- Open access
- OpenAlex
- https://openalex.org/W2012251902
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4389441
Keywords
Antibiotics, Lipid II, Antibiotic resistance, Bacteria, Microbiology
References
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- Review and re-analysis of domain-specific 16S primers.
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- A sustainable model for antibiotics
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- The core root microbiome of sugarcanes cultivated under varying nitrogen fertilizer application.
- A Perspective on the Trends and Challenges Facing Porphyrin-Based Anti-Microbial Materials.
- High-throughput strategies for the discovery and engineering of enzymes for biocatalysis
- Glycopeptide resistance: Links with inorganic phosphate metabolism and cell envelope stress.
- New approaches to antibiotic discovery
- Novel compounds targeting the enterohemorrhagic Escherichia coli type three secretion system reveal insights into mechanisms of secretion inhibition
- A Therapeutic Connection between Dietary Phytochemicals and ATP Synthase
- Strategies to diversify natural products for drug discovery
- Discovery and development of new antibacterial drugs: learning from experience?
- Advancement of the 5-Amino-1-(Carbamoylmethyl)-1H-1,2,3-Triazole-4-Carboxamide Scaffold to Disarm the Bacterial SOS Response
- Chemical Ecology of Streptomyces albidoflavus Strain A10 Associated with Carpenter Ant Camponotus vagus
- The direct anti-MRSA effect of emodin via damaging cell membrane
- Bacterial Biofilm Inhibition and Antifungal Activity of Neotropical Plants
- Rapid synthesis and antimicrobial activity of novel 4-oxazolidinone heterocycles.
- The global challenge of new classes of antibacterial agents: an industry perspective.
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