Current status of gene therapy for cancer
Explore this paper's citation graph
Summary
Cancer gene therapy has made remarkable progress in the improvement/refinement of existing strategies and delivery systems and the field is moving toward a therapeutic option, which will also be applicable for the treatment of disseminated metastases.
- Type
- review
- Published
- 2013-11-01
- Cited by
- 57
- References
- 32
- OpenAlex
- https://openalex.org/W2011457202
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9717133
Keywords
Oncolytic virus, Medicine, Genetic enhancement, Clinical trial, Gene delivery
References
- The development of gene therapy: from monogenic recessive disorders to complex diseases such as cancer.
- Inhibitory effects of c-erbB-2 antisense oligonucleotide transfection on uterine endometrial cancer Ishikawa cell lines.
- Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans
- Chemovirotherapy for head and neck squamous cell carcinoma with EGFR-targeted and CD/UPRT-armed oncolytic measles virus
- Phase I Clinical Trial of Systemically Administered TUSC2(FUS1)-Nanoparticles Mediating Functional Gene Transfer in Humans
- Gene therapy clinical trials worldwide to 2012 – an update
- Causes and consequences of microRNA dysregulation in cancer
- Phase I Study of the c-raf-1 Antisense Oligonucleotide ISIS 5132 in Combination with Carboplatin and Paclitaxel in Patients with Previously Untreated, Advanced Non-small Cell Lung Cancer
- Phase I study of a systemically delivered p53 nanoparticle in advanced solid tumors.
- Phase I clinical development of Atu027, a siRNA formulation targeting PKN3 in patients with advanced solid tumors.
- Therapeutic effects of STAT3 decoy oligodeoxynucleotide on human lung cancer in xenograft mice
- Xenogeneic Human p53 DNA Vaccination by Electroporation Breaks Immune Tolerance to Control Murine Tumors Expressing Mouse p53
- Functionalized Graphene Oxide Mediated Adriamycin Delivery and miR-21 Gene Silencing to Overcome Tumor Multidrug Resistance In Vitro
- DNA Vaccines: Developing New Strategies against Cancer
- Local gene therapy of solid tumors with GM-CSF and B7-1 eradicates both treated and distal tumors
- Ultrasound-Targeted Microbubble Destruction to Deliver siRNA Cancer Therapy
- A review of nanocarriers for the delivery of small interfering RNA.
- Novel Clostridium perfringens enterotoxin suicide gene therapy for selective treatment of claudin-3- and -4-overexpressing tumors
- MiR-181a enhances drug sensitivity in mitoxantone-resistant breast cancer cells by targeting breast cancer resistance protein (BCRP/ABCG2)
- Local and Distant Immunity Induced by Intralesional Vaccination with an Oncolytic Herpes Virus Encoding GM-CSF in Patients with Stage IIIc and IV Melanoma
Cited by
- Antibody-targeted nanoparticles for cancer treatment.
- The Development of Interferon-based Gene Therapy for BCG Unresponsive Bladder Cancer: From Bench to Bedside
- UPRT, a suicide-gene therapy candidate in higher eukaryotes, is required for Drosophila larval growth and normal adult lifespan
- Arming oncolytic viruses to leverage antitumor immunity
- An Enterovirus-Like RNA Construct for Colon Cancer Suicide Gene Therapy
- Trial Watch:
- MicroRNAs and oncolytic viruses.
- Inhibition of human bladder cancer growth by a suicide gene delivered by JC polyomavirus virus-like particles in a mouse model.
- Prognostic value of miR-26a and HMGA1 in urothelial bladder cancer.
- A family of cationic polyamides for in vitro and in vivo gene transfection.
- Key points of basic theories and clinical practice in rAd-p53 (Gendicine™) gene therapy for solid malignant tumors
- Bioreducible dextran-polyethylenimine conjugates regulate transgene expression distribution in vivo.
- Electrospun nanofibers as versatile interfaces for efficient gene delivery
- Mesenchymal stem cells genetically modified by lentivirus-mediated interleukin-12 inhibit malignant ascites in mice
- Multifunctional cationic polyurethanes designed for non-viral cancer gene therapy.
- Innovation status of gene therapy for breast cancer.
- Efficient inhibition of ovarian cancer by degradable nanoparticle-delivered survivin T34A gene
- Biodegradable gadolinium-chelated cationic poly(urethane amide) copolymers for gene transfection and magnetic resonance imaging.
- Endocytosis in gene therapy with non-viral vectors
- Design of virus-based nanomaterials for medicine, biotechnology, and energy
Related papers
- Oncolytic virus-based suicide gene therapy for cancer treatment: a perspective of the clinical trials conducted at Henry Ford Health
- In Vivo Evaluation of a Cancer Therapy Strategy Combining HSV1716-Mediated Oncolysis with Gene Transfer and Targeted Radiotherapy
- Shedding light on tumor targeting by adenovirus.
- Drug delivery system for cancer gene therapy - A review
- Gene and Cell Therapy: Therapeutic Mechanisms and Strategies, Second Edition, Revised and Expanded
- [Gene therapy for castration resistant prostate cancer].
- Recent advances in the development of gene delivery systems