Phosphorylation of G-protein alpha-subunits in intact adipose cells: evidence against a mediating role in insulin-dependent metabolic effects.

Keywords

Phosphoprotein, Immunoprecipitation, Antiserum, Phosphorylation, Protein subunit

References

• Kinetic parameters of transport of 3-O-methylglucose and glucose in adipocytes.Richard R. Whitesell, Jørgen Gliemann — 1979
• Insulin exerts actions through a distinct species of guanine nucleotide regulatory protein: inhibition of adenylate cyclase.C M Heyworth, Miles D. Houslay — 1983
• Identification of a cellular 110 000-Da protein substrate for the insulin-receptor kinase.Jean‐Louis Sadoul, Jean‐François Peyron, Robert Ballotti — 1985
• Evidence that insulin activates fat-cell acetyl-CoA carboxylase by increased phosphorylation at a specific site.Roger W. Brownsey, R M Denton — 1982
• The glucose transporter in 3T3-L1 adipocytes is phosphorylated in response to phorbol ester but not in response to insulin.E. Michael Gibbs, W. Jeffrey Allard, Gustav E. Lienhard — 1986
• cAMP-dependent protein kinase and lipolysis in rat adipocytes. I. Cell preparation, manipulation, and predictability in behavior.R C Honnor, Gurpreet S. Dhillon, Constantine Londos — 1985
• Insulin-dependent phosphorylation of GTP-binding proteins in phospholipid vesicles.Jerzy Krupiński, Rama Rajaram, Margot Lakonishok — 1988
• Regulation of insulin-stimulated glucose transport in the isolated rat adipocyte. cAMP-independent effects of lipolytic and antilipolytic agents.M. Kuroda, R C Honnor, Samuel W. Cushman — 1987
• Activity and phosphorylation state of glucose transporters in plasma membranes from insulin-, isoproterenol-, and phorbol ester-treated rat adipose cells.Hans‐Georg Joost, Teresa M. Weber, Samuel W. Cushman — 1987
• An endogenous substrate for the insulin receptor-associated tyrosine kinase.R W Rees-Jones, Simeon I. Taylor — 1985
• Phosphorylation of hormone-sensitive lipase by cyclic AMP-dependent protein kinase.Peter Strålfors, Per Belfrage — 1983
• Insulin inhibits pertussis toxin-catalyzed ADP-ribosylation of G-proteins. Evidence for a novel interaction between insulin receptors and G-proteins.Paul Rothenberg, C. Ronald Kahn — 1988
• Insulin-stimulated glucose transport in rat adipose cells. Modulation of transporter intrinsic activity by isoproterenol and adenosine.Hans‐Georg Joost, Teresa M. Weber, Samuel W. Cushman — 1986
• The Metabolism of Isolated Fat Cells: I. Effects of Hormones on Glucose Metabolism and LipolysisMartin Rodbell — 1964
• Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor.Masato Kasuga, F. Anders Karlsson, C. Ronald Kahn — 1982
• Immunochemical detection of the alpha-subunit of the G-protein, GZ, in membranes and cytosols of mammalian cells.Karsten Spicher, Klaus‐Dieter Hinsch, Heinrich Gausepohlꝉ — 1988
• Adipocyte plasma membranes contain two Gi subtypes but are devoid of GoKlaus‐Dieter Hinsch, Walter Rosenthal, Karsten Spicher — 1988
• Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cellsMorris F. White, Ruth Maron, C. Ronald Kahn — 1985
• The insulin receptor tyrosyl kinase phosphorylates holomeric forms of the guanine nucleotide regulatory proteins Gi and GoRichard M. O’Brien, Miles D. Houslay, Graeme Milligan — 1987
• Insulin-activated tyrosine phosphorylation of a 15-kilodalton protein in intact 3T3-L1 adipocytes.Michel Bernier, D M Laird, M. Daniel Lane — 1987

Cited by

• The regulation of glucose transport in insulin-sensitive cellsHans‐Georg Joost, Teresa M. Weber — 1989
• Regulation of leptin release by insulin, glucocorticoids, G(i)-coupled receptor agonists, and pertussis toxin in adipocytes and adipose tissue explants from obese humans in primary culture.Alie Kanu, John N. Fain, Suleiman W. Bahouth — 2003

Related papers

• Antiserum to polyacrylamide gel-purified simian virus 40 T antigen.R. B. Carroll, Steven M. Goldfine, José A. Melero — 1978
• Characterization of a rabbit polyclonal antibody against threonine-AMPylationYi-Heng Hao, Trinette Chuang, Haydn L. Ball — 2010
• Studies on the effect of specific antisera on the metabolism of cellular antigens. I. Isolation of thymus leukemia antigens.Alice L. Yu, Edward P. Cohen — 1974
• Association of Rabies Virus Nominal Phosphoprotein (P) with Viral Nucleocapsid (NC) Is Enhanced by Phosphorylation of the Viral Nucleoprotein (N)Harufusa Toriumi, Akihiko Kawai — 2004
• Heterotrimeric G proteins in C. elegans.Carol Bastiani — 2006
• RGS family members: GTPase-activating proteins for heterotrimeric G-protein α-subunitsNed Watson, Maurine E. Linder, Kirk M. Druey — 1996
• Structural Determinants Involved in the Formation and Activation of G Protein βγ DimersWilliam E. McIntire — 2009
• G protein diversity: a distinct class of alpha subunits is present in vertebrates and invertebrates.M Strathmann, Melvin I. Simon — 1990