Identification of a cellular 110 000-Da protein substrate for the insulin-receptor kinase.
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Summary
The present identification of an endogenous substrate for the insulin-receptor kinase could suggest that some, if not all, effects of insulin may be mediated through activation of this kinase.
- Type
- article
- Published
- 1985-05-01
- Cited by
- 44
- References
- 0
- Access
- Open access
- OpenAlex
- https://openalex.org/W82722785
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:37064868
Keywords
Autophosphorylation, IRS2, Insulin receptor, Insulin receptor substrate, GRB10
References
No references recorded for this paper.
Cited by
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- The insulin receptor: signalling mechanism and contribution to the pathogenesis of insulin resistance
- Insulin Resistance: A Look at the Role of Insulin Receptor Kinase
- Localization of a putative cell adhesion molecule (gp110) in Wistar and Fischer rat tissues
- Bile duct ligation-induced redistribution of canalicular antigen in rat hepatocyte plasma membranes demonstrated by immunogold quantitation
- Characteristics of calmodulin phosphorylation by the insulin receptor kinase.
- Regulation of the protein kinase activity of the human insulin receptor.
- Insulin induced phosphorylation and activation of the cGMP-inhibited cAMP phosphodiesterase in human platelets.
- The regulation of glucose transport in insulin-sensitive cells
- Phosphorylation of G-protein alpha-subunits in intact adipose cells: evidence against a mediating role in insulin-dependent metabolic effects.
- Insulin receptors in lizard brain and liver: structural and functional studies of α and β subunits demonstrate evolutionary conservation
- Role of kinases in insulin stimulation of glucose transport
- Appearance of a functional insulin receptor during rabbit embryogenesis
- Insulin receptors and the clinician.
- Insulin action in vivo on a growth-related protein kinase in lactating mouse mammary gland.
- Insulin receptor: tyrosine kinase activity and insulin action.
- The insulin receptor kinase.
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