Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis

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Summary

In conclusion, these data are compatible with the hypothesis that apoptotic ΔΨ m disruption is mediated by the formation of PT pores and that PT‐mediated ΔΩ mruption is a critical event of the apoptotic cascade.

Type
article
Published
1996-04-08
Cited by
468
References
40
Access
Open access

Keywords

Mitochondrial permeability transition pore, Apoptosis, Cell biology, Membrane potential, Mitochondrion

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