DrugBank: a knowledgebase for drugs, drug actions and drug targets

Keywords

DrugBank, Drug, Drug discovery, Drug action, ADME

References

• Application of Associative Neural Networks for Prediction of Lipophilicity in ALOGPS 2.1 ProgramIgor V. Tetko, Vsevolod Yu. Tanchuk — 2002
• Methods for predicting human drug metabolism.Larry J. Jolivette, Sean Ekins — 2007
• BioMoby extensions to the Taverna workflow management and enactment softwareEdward Kawas, Martin Senger, Mark D. Wilkinson — 2006
• How many drug targets are there?John P. Overington, Bissan Al‐Lazikani, Andrew L. Hopkins — 2006
• Recent advances in computational prediction of drug absorption and permeability in drug discovery.Tingjun Hou, Junmei Wang, Wei Zhang — 2006
• The PharmGKB: integration, aggregation, and annotation of pharmacogenomic data and knowledgeAmy Hodge, Russ B. Altman, Teri E. Klein — 2007
• The druggable genome: an update.Andreas Russ, Stefan Lampel — 2005
• Functional annotation of proteomic sequences based on consensus of sequence and structural analysisDavid H. Kitson — 2002
• TTD: Therapeutic Target DatabaseX. Chen — 2002
• TarFisDock: a web server for identifying drug targets with docking approachHongyang Li, Zengqiang Gao, Ling Kang — 2006
• Protein annotation by EBIMedDietrich Rebholz‐Schuhmann, Harald Kirsch, Miguel Arregui — 2006
• Discovering drug targets through the web.David S. Wishart — 2007
• Drugs, their targets and the nature and number of drug targetsPeter Imming, Christian Sinning, Achim Meyer — 2006
• The druggable genomeAndrew L. Hopkins, Colin R. Groom — 2002
• GeneCards: a novel functional genomics compendium with automated data mining and query reformulation supportMichael Rebhan, Vered Chalifa‐Caspi, Jaime Prilusky — 1998
• The European Bioinformatics Institute's data resources: towards systems biologyCath Brooksbank — 2004
• New uses for old drugsCurtis R. Chong, David Sullivan — 2007
• Database resources of the National Center for Biotechnology Information: updateDavid Wheeler — 2004
• Rapid Identification of P-glycoprotein Substrates and InhibitorsCheng Chang, Praveen M. Bahadduri, James E. Polli — 2006
• Analysis of genomic and proteomic data using advanced literature mining.Yanhui Hu, Lisa M. Hines, Haifeng Weng — 2003

Cited by

• Three-component synthesis of C2F5-substituted pyrazoles from C2F5CH2NH2·HCl, NaNO2 and electron-deficient alkynesPavel K. Mykhailiuk — 2015
• Exploring the Relationship Between Drug Side-Effects and Therapeutic IndicationsPing Zhang, Fei Wang, Jianying Hu — 2013
• Superimposé: a 3D structural superposition serverMeng‐Fen Yen, Yen, Meng-Feng — 2008
• The analysis of the drug–targets based on the topological properties in the human protein–protein interaction network健 松井 — 2009
• Properties and identification of antibiotic drug targets晃 浅野 — 2010
• Exploring schizophrenia drug-gene interactions through molecular network and pathway modeling.Daniel K. Putnam, Jingchun Sun, Zhongming Zhao — 2011
• Pharmacogenetics and forensic toxicology.Sergio Guevara, Javier Laborde — 2010
• A new approach to assess and predict the functional roles of proteins across all known structuresSantiago Javier Armesilla Conde — 2011
• Accelerated Identification of Proteins by Mass Spectrometry by Employing Covalent Pre-Gel Staining with Uniblue AChristian Bugge Henriksen, Jesper Rasmussen, Martin Heide Jørgensen — 2012
• DTome: a web-based tool for drug-target interactome constructionElham Bagheri — 2012
• Vitexicarpin Acts as a Novel Angiogenesis Inhibitor and Its Target NetworkXavier Panadés Gella — 2013
• Integrative systems biology approaches to identify and prioritize disease and drug candidate genes.Vivek Kaimal, Divya Sardana, Eric E. Bardes — 2011
• Structural properties and interaction energies affecting drug design. An approach combining molecular simulations, statistics, interaction energies and neural networksВ. С. Кузнецова, В. Г. Куленко — 2015
• The Chemical Validation and Standardization Platform (CVSP): large-scale automated validation of chemical structure datasetsChristiano Cruz Ambros — 2015
• Structure of the Varicella Zoster Virus Thymidylate Synthase Establishes Functional and Structural Similarities as the Human Enzyme and Potentiates Itself as a Target of BrivudineHerbert Grziwotz — 2015
• Drug‐Target NetworksJuan Torres Noguera — 2010
• IDICAP: A Novel Tool for Integrating Drug Intervention Based on Cancer PanelEsti Imaniatun — 2016
• Chembench: A Publicly-Accessible, Integrated Cheminformatics PortalMarghanita da Cruz — 2017
• Virtual screening and experimental validation identify novel modulators of nuclear receptor RXRα from Drugbank database.徐猛, 李新营 — 2017
• A retrosynthetic analysis algorithm implementationBrahma Chellaney — 2019

Related papers

• Exploring chemical space for drug discovery using the chemical universe database.Jean‐Louis Reymond, Mahendra Awale — 2012
• DrugBank: a comprehensive resource for in silico drug discovery and explorationDavid S. Wishart — 2005
• DrugRepV: a compendium of repurposed drugs and chemicals targeting epidemic and pandemic virusesAkanksha Rajput, Archit Kumar, Kirti Megha — 2021
• The Mechanism of Compound Danshen Dripping Pills in the Treatment of Diabetic Retinopathy Based on Network Pharmacology and Molecular DockingXuedong An, Liyun Duan, YueHong Zhang — 2021
• Comparing the Chemical Structure and Protein Content of ChEMBL, DrugBank, Human Metabolome Database and the Therapeutic Target DatabaseChristopher Southan, Markus Sitzmann, Sorel Mureşan — 2013
• Screening of β1- and β2-Adrenergic Receptor Modulators through Advanced Pharmacoinformatics and Machine Learning ApproachesMd Ataul Islam, V.P. Subramanyam Rallabandi, Sameer Mohammed — 2021
• CS‐MINER: A Tool for Association Mining in Binding‐DatabaseAhmad Mani‐Varnosfaderani, Abolfazl Valadkhani, Mehdi Jalali‐Heravi — 2015
• TCMID: traditional Chinese medicine integrative database for herb molecular mechanism analysisRuichao Xue, Zhao Fang, Meixia Zhang — 2012