The biological functions of T helper 17 cell effector cytokines in inflammation.
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Summary
The effector cytokines of Th17 cells mediate the crucial crosstalk between immune system and tissues, and play indispensable roles in tissue immunity.
- Type
- review
- Published
- 2008-04-11
- Cited by
- 1,812
- References
- 167
- Access
- Open access
- OpenAlex
- https://openalex.org/W2004186675
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:6355961
Keywords
Biology, Effector, Crosstalk, Immune system, Immunology
References
- IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration.
- IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6.
- IL-17 family cytokines and the expanding diversity of effector T cell lineages.
- IL-17A-producing neutrophil-regulatory Tn lymphocytes
- Interleukin 20: discovery, receptor identification, and role in epidermal function.
- Act1 Adaptor Protein Is an Immediate and Essential Signaling Component of Interleukin-17 Receptor*
- IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways.
- Expression and regulation of IL-22 in the IL-17-producing CD4+ T lymphocytes
- IL-22 Induces Lipopolysaccharide-Binding Protein in Hepatocytes: A Potential Systemic Role of IL-22 in Crohn’s Disease
- IL-17 Receptor Knockout Mice Have Enhanced Myelotoxicity and Impaired Hemopoietic Recovery Following Gamma Irradiation
- Acinar Cells of the Pancreas Are a Target of Interleukin-22
- The Effects of IL-20 Subfamily Cytokines on Reconstituted Human Epidermis Suggest Potential Roles in Cutaneous Innate Defense and Pathogenic Adaptive Immunity in Psoriasis
- Identification of the IL-17 Receptor Related Molecule IL-17RC as the Receptor for IL-17F
- Messenger RNA sequence and expression of rat pancreatitis-associated protein, a lectin-related protein overexpressed during acute experimental pancreatitis.
- IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-κB- and PI3-kinase/Akt-dependent pathways
- IL-17 stimulates granulopoiesis in mice: use of an alternate, novel gene therapy-derived method for in vivo evaluation of cytokines.
- IL-22 Inhibits Epidermal Differentiation and Induces Proinflammatory Gene Expression and Migration of Human Keratinocytes1
- New IL-17 Family Members Promote Th1 or Th2 Responses in the Lung: In Vivo Function of the Novel Cytokine IL-251
- Differential Effects of IL-21 during Initiation and Progression of Autoimmunity against Neuroantigen1
- Microbial Lipopeptides Induce the Production of IL-17 in Th Cells1
Cited by
- Wolbachia endosymbiont of Onchocerca volvulus: driver of immunopathology and target for therapy
- Epigenetic changes in inflammatory and autoimmune diseases.
- The interleukin‐17 pathway is involved in human alcoholic liver disease
- Critical Role of TCF-1 in Repression of the IL-17 Gene
- The Roles and Perspectives of Toll-Like Receptors and CD4+ Helper T Cell Subsets in Acute Viral Encephalitis
- Candida albicans and Candida parapsilosis induce different T-cell responses in human peripheral blood mononuclear cells.
- IL-1 and T Helper Immune Responses
- A new case of Job's syndrome at the clinic: a diagnostic challenge.
- Cytokines in Common Variable Immunodeficiency as Signs of Immune Dysregulation and Potential Therapeutic Targets – A Review of the Current Knowledge
- IL-17/IL-10 double-producing T cells: new link between infections, immunosuppression and acute myeloid leukemia
- Cytokines and Immune Responses in Murine Atherosclerosis.
- IL-22 regulation of functional gene expression in salivary gland cells
- Tetracyclic dihydronaphthalene derivatives via gold-catalyzed aminative homodimerization of ortho-alkynylbenzaldehydes.
- Methods of Controlling Invasive Fungal Infections Using CD8+ T Cells
- An acute challenge with a deoxynivalenol-contaminated diet has short- and long-term effects on performance and feeding behavior in finishing pigs.
- Effects of Acute Alcohol Exposure on Post Burn Intestinal Immunity: Role of IL-23
- Interleukin-4 induced leukocyte differentiation
- Imbalance of Th17 to Th1 cells in Behçet's disease.
- Homing in on Acute Graft vs. Host Disease: Tissue-Specific T Regulatory and Th17 Cells
- Macrophages and neutrophils as major source of B-cells activating factors in H. pylori associated diseases
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