IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration.
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Summary
IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and IEC migration, which suggests an important function in intestinal inflammation and wound healing.
- Type
- article
- Published
- 2006-04-01
- Cited by
- 579
- References
- 59
- Access
- Open access
- OpenAlex
- https://openalex.org/W16537974
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21313362
Keywords
Digital subscriber line, Cable modem, Cable Internet access, Telecommunications, Internet access
References
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- SOCS-1 inhibits expression of the antiviral proteins 2',5'-OAS and MxA induced by the novel interferon-lambdas IL-28A and IL-29.
- IL-10 and its related cytokines for treatment of inflammatory bowel disease.
- p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease.
- Acinar Cells of the Pancreas Are a Target of Interleukin-22
- Active movement of T cells away from a chemokine
- IL-22 Inhibits Epidermal Differentiation and Induces Proinflammatory Gene Expression and Migration of Human Keratinocytes1
- Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
- A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
- Protein Kinase C and ERK Activation Are Required for TFF- peptide-stimulated Bronchial Epithelial Cell Migration and Tumor Necrosis Factor-α-induced Interleukin-6 (IL-6) and IL-8 Secretion*
- IL-22, a Th1 cytokine that targets the pancreas and select other peripheral tissues.
- Cytokine modulation of intestinal epithelial cell restitution: central role of transforming growth factor beta.
- Identification of the Functional Interleukin-22 (IL-22) Receptor Complex
- Fractalkine is an epithelial and endothelial cell-derived chemoattractant for intraepithelial lymphocytes in the small intestinal mucosa.
- Interleukin-22 activates STAT3 and induces IL-10 by colon epithelial cells.
- IL-10 subfamily members: IL-19, IL-20, IL-22, IL-24 and IL-26.
- IL-22 increases the innate immunity of tissues.
- Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.
- The immunological and genetic basis of inflammatory bowel disease
- The expanded family of class II cytokines that share the IL‐10 receptor‐2 (IL‐10R2) chain
Cited by
- IL-22 promotes the migration and invasion of gastric cancer cells via IL-22R1/AKT/MMP-9 signaling.
- Up-regulated Reg proteins induced by Interleukin-22 treatment ameliorate acute liver injury in rat model.
- Interleukin-22 – Freund oder Feind?
- Th17 T cells: linking innate and adaptive immunity.
- Pyroglutamate and O-Linked Glycan Determine Functional Production of Anti-IL17A and Anti-IL22 Peptide-Antibody Bispecific Genetic Fusions
- IL-22 regulation of functional gene expression in salivary gland cells
- Immunological profiling of patients with ulcerative colitis leads to identification of two inflammatory conditions and CD1a as a disease marker
- IL‐22 promotes Fas expression in oligodendrocytes and inhibits FOXP3 expression in T cells by activating the NF‐&kgr;B pathway in multiple sclerosis
- Molecular characteristics of rhesus macaque interleukin‐22: cloning, in vitro expression and biological activities
- IL‐22 sustains epithelial integrity in progressive kidney remodeling and fibrosis
- The Effect of IL-26 on TNF-α-Induced CXCL8 Responses by Colonic Epithelial Cell Lines
- The development of colitis in Il10−/− mice is dependent on IL-22
- IL-22: Implications for Liver Ischemia/Reperfusion Injury
- Role of IL-22 in microbial host defense.
- Interleukin-10 in the Control of Tumor Immunity and Autoimmunity.
- Lymphoid like stromal cells in a model of tertiary lymphoid organ formation
- The role of IL-22 produced by Th17 cells in Type 1 Diabetes
- The biology and functions of Th22 cells.
- Th17 differentiation and their pro-inflammation function.
- Interleukin-22 Promotes T Helper 1 (Th1)/Th17 Immunity in Chlamydial Lung Infection
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