Myeloid-derived-suppressor cells as regulators of the immune system
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Summary
The origin, mechanisms of expansion and suppressive functions of MDSCs, as well as the potential to target these cells for therapeutic benefit are discussed.
- Type
- review
- Published
- 2009-03-01
- Cited by
- 6,878
- References
- 138
- OpenAlex
- https://openalex.org/W2004150448
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:39550453
Keywords
Myeloid-derived Suppressor Cell, Immune system, Suppressor, Biology, Inflammation
References
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Cited by
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- The role of LL-37 in prostate cancer and its potential as a therapeutic target
- Systematic Assessment of the Contribution of Superantigens to Nasopharyngeal Colonization in a Mouse Model of Streptococcal Infection
- Analyzing cell death events in cultured leukocytes.
- TNFR1-Dependent Regulation of Myeloid Cell Function in Experimental Autoimmune Uveoretinitis1
- COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function
- Inflammatory Blood Monocytes Contribute to Tumor Development and Represent a Privileged Target To Improve Host Immunosurveillance
- Messenger RNA-based Vaccines With Dual Activity Induce Balanced TLR-7 Dependent Adaptive Immune Responses and Provide Antitumor Activity
- Photodynamic Therapy Enhancement of Anti-Tumor Immunity
- Immature myeloid cells accumulate in mouse placenta and promote angiogenesis.
- Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma.
- Enhanced Th17-Cell Responses Render CCR2-Deficient Mice More Susceptible for Autoimmune Arthritis
- Pathway-Based Evaluation in Early Onset Colorectal Cancer Suggests Focal Adhesion and Immunosuppression along with Epithelial-Mesenchymal Transition
- Exosomes in Cancer Microenvironment and Beyond: have we Overlooked these Extracellular Messengers?
- Pulmonary macrophage subpopulations in the induction and resolution of acute lung injury.
- Increased frequency and clinical significance of myeloid-derived suppressor cells in human colorectal carcinoma.
- Differing Patterns of Circulating Regulatory T-Cells and Myeloid Derived Suppressor Cells in Metastatic Melanoma Patients Receiving Anti-CTLA4 Antibody and Interferon-α or TLR-9 Agonist and GM-CSF with Peptide Vaccination
- Single low-dose cyclophosphamide combined with interleukin-12 gene therapy is superior to a metronomic schedule in inducing immunity against colorectal carcinoma in mice
- Ly6C+Ly6G− Myeloid‐derived suppressor cells play a critical role in the resolution of acute inflammation and the subsequent tissue repair process after spinal cord injury
- Neutrophils confer T cell resistance to MDSC-mediated suppression to promote chronic inflammation
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