The influence of lipoxygenase inhibitors on the in vitro production of human leukocytic pyrogen and lymphocyte activating factor (interleukin-1).
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Summary
Findings indicate that a product of arachidonate lipoxygenase is important in the sequence of events underlying cell activation for the production of human LP/LAF/IL-1.
- Type
- article
- Published
- 1984-01-01
- Cited by
- 220
- References
- 34
- OpenAlex
- https://openalex.org/W2003938316
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:6855975
Keywords
In vitro, Lipoxygenase, Lymphocyte, Chemistry, Interleukin
References
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- Monohydroxyeicosatetraenoic acids (HETEs) induce degranulation of human neutrophils.
- On the specificity of the oxygenation of unsaturated fatty acids catalyzed by soybean lipoxidase.
- Effect of inhibitors of arachidonic acid metabolism on mitogenesis in human lymphocytes: possible role of thromboxanes and products of the lipoxygenase pathway.
- Endogenous pyrogens made by rabbit peritoneal exudate cells are identical with lymphocyte-activating factors made by rabbit alveolar macrophages.
- Arachidonic acid 15-lipoxygenase from rabbit peritoneal polymorphonuclear leukocytes. Partial purification and properties.
- Possible role of arachidonic acid and its metabolites in mediator release from rat mast cells.
- The effects of acetaminophen and sodium salicylate on the release and activity of leukocytic pyrogen in the cat.
- Inactivation of slow reacting substance of anaphylaxis (SRS-A) by lipoxidase.
- Mouse peritoneal macrophages release leukotriene C in response to a phagocytic stimulus.
- Effects of cyclooxygenase inhibitors and prostaglandin E2 on macrophage activation in vitro.
- A radioimmunoassay for thromboxane B2.
- DEMONSTRATION AND CHARACTERIZATION OF TWO DISTINCT HUMAN LEUKOCYTIC PYROGENS
- Human leukocytic pyrogen: purification and development of a radioimmunoassay.
- The inhibitory effects of BW 755C on arachidonic acid metabolism in human polymorphonuclear leukocytes
- The role of macrophages in the acute-phase response: SAA inducer is closely related to lymphocyte activating factor and endogenous pyrogen.
- Ability of human leukocytic pyrogen to enhance phytohemagglutinin induced murine thymocyte proliferation.
- Studies on steroid fever. II. Pyrogenic and anti-pyrogenic activity in vitro of some endogenous steroids of man.
- Molecular basis of fever in humans.
- New Devices and Methods for Long-term Vascular Access for Blood Sampling and Insulin Infusion
Cited by
- Transcription, translation and secretion of interleukin 1 and tumor necrosis factor: effects of tebufelone, a dual cyclooxygenase/5‐lipoxygenase inhibitor
- Leukotrienes do not regulate interleukin 1 production by activated macrophages.
- Effect of steroidal anti-inflammatory drugs on Escherichia coli endotoxin-induced mastitis in the cow.
- The metabolism and immunology of bone.
- LTB4 and PAF in the cytokine network.
- Studies on the production of endogenous pyrogen by rabbit monocytes: the role of calcium and cyclic nucleotides.
- The role of 13-hydroxylinoleic acid in the activation of macrophages by lipopolysaccharide.
- Bacterial endotoxin: Chemical constitution, biological recognition, host response, and immunological detoxification.
- Eicosanoide und Phospholipasen
- The Pharmacology of Lymphocytes
- Biological activities residing in the Fc region of immunoglobulin.
- Modulation of macrophage antitumor cytostasis by endogenous leukotrienes
- Glucocorticoids inhibit transcriptional and post-transcriptional expression of interleukin 1 in U937 cells.
- Interleukin-1 and interleukin-1 antagonism.
- Modulation of cytokine function: therapeutic applications.
- Immune-modulating effects of polyunsaturated fatty acids : focus on dihomo-G-linolenic acid
- Ex vivo lipopolysaccharide‐induced interleukiri‐1 secretion from murine peritoneal macrophages inhibited by probucol, a hypocholesterolemic agent with antioxidant properties
- Dietary fish oil supplementation alters LTB4:LTB5 ratios but does not affect the expression of acute graft versus host disease in mice.
- Biochemical, physiological and clinical aspects of endotoxemia.
- Plasma exchange, but not extracorporal recirculation nor removal of white blood cells, depresses plasma levels of IL-1 during severe gram-negative septicemia
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